S1PR4
sphingosine-1-phosphate receptor 4
Summary
This gene is a member of the endothelial differentiation, G-protein-coupled (EDG)) receptor gene family. EDG receptors bind lysophospholipids or lysosphingolipids as ligands, and are involved in cell signalling in many different cell types. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue. [provided by RefSeq, Jul 2008]
Known Variants42 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs755933228 | 19:3,178,802 | G/A | — | likely benign |
| rs750183249 | 19:3,178,840 | C/T | — | uncertain significance |
| rs575226710 | 19:3,178,845 | G/A | — | likely benign |
| rs542214597 | 19:3,178,858 | G/A | — | uncertain significance |
| rs1915485186 | 19:3,178,876 | A/G | — | uncertain significance |
| rs746634486 | 19:3,178,899 | G/A | — | uncertain significance |
| rs754628854 | 19:3,178,939 | G/A | — | uncertain significance |
| rs769182864 | 19:3,178,948 | C/T | — | uncertain significance |
| rs1210979921 | 19:3,179,005 | C/A | — | uncertain significance |
| rs749257001 | 19:3,179,023 | G/A | — | uncertain significance |
| rs144002553 | 19:3,179,051 | C/T | — | likely benign |
| rs34573539 | 19:3,179,075 | G/A | — | likely benign |
| rs79175715 | 19:3,179,081 | G/A | — | likely benign |
| rs1373068892 | 19:3,179,091 | G/A | — | uncertain significance |
| rs755686122 | 19:3,179,104 | T/C | — | uncertain significance |
| rs202230080 | 19:3,179,125 | G/A | — | uncertain significance |
| rs373222281 | 19:3,179,135 | C/T | — | likely benign |
| rs199739701 | 19:3,179,136 | G/A | — | uncertain significance |
| rs200975604 | 19:3,179,181 | G/A | — | uncertain significance |
| rs139895721 | 19:3,179,212 | G/A | — | uncertain significance |
| rs151055104 | 19:3,179,253 | G/A | — | uncertain significance |
| rs779334115 | 19:3,179,254 | G/C | — | uncertain significance |
| rs374345189 | 19:3,179,274 | G/A | — | uncertain significance |
| rs2512062013 | 19:3,179,319 | G/A | — | uncertain significance |
| rs750433769 | 19:3,179,397 | C/T | — | uncertain significance |
| rs138558077 | 19:3,179,398 | G/A | — | uncertain significance |
| rs751701620 | 19:3,179,430 | G/A | — | likely benign |
| rs146465201 | 19:3,179,433 | G/A | — | likely benign |
| rs2512062191 | 19:3,179,482 | A/C | — | uncertain significance |
| rs200307755 | 19:3,179,506 | G/A | — | uncertain significance |
| rs773473010 | 19:3,179,512 | C/T | — | uncertain significance |
| rs201614366 | 19:3,179,533 | G/A | — | uncertain significance |
| rs199734577 | 19:3,179,613 | G/T | — | uncertain significance |
| rs2512062461 | 19:3,179,760 | T/C | — | uncertain significance |
| rs757142499 | 19:3,179,788 | G/T | — | uncertain significance |
| rs376837194 | 19:3,179,808 | C/T | — | uncertain significance |
| rs370140415 | 19:3,179,844 | G/A | — | uncertain significance |
| rs3746072 | 19:3,179,884 | G/T | missense variant | — |
| rs565159263 | 19:3,179,899 | G/A | — | uncertain significance |
| rs368502121 | 19:3,179,903 | G/C | — | uncertain significance |
| rs754806689 | 19:3,179,905 | G/A | — | uncertain significance |
| rs182269256 | 19:3,179,906 | G/A | — | benign |
Gene information from NCBI Gene. Variant classifications from ClinVar.