SAC3D1
SAC3 domain containing 1
Summary
Predicted to be involved in centrosome duplication and spindle assembly. Predicted to act upstream of or within negative regulation of receptor signaling pathway via JAK-STAT and regulation of immune response. Predicted to be located in microtubule cytoskeleton. Predicted to be part of protein-containing complex. Predicted to be active in centrosome; nucleus; and spindle. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants28 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2458589 | 11:64,806,498 | C/T | upstream gene variant | — |
| rs756082534 | 11:64,808,825 | G/C | — | uncertain significance |
| rs369250577 | 11:64,809,041 | G/T | — | likely benign |
| rs767063735 | 11:64,809,048 | C/T | — | uncertain significance |
| rs956362077 | 11:64,809,063 | T/G | — | uncertain significance |
| rs1380533484 | 11:64,809,119 | G/A | — | uncertain significance |
| rs1346159122 | 11:64,809,125 | G/A | — | uncertain significance |
| rs777894075 | 11:64,809,134 | G/A | — | uncertain significance |
| rs1946608303 | 11:64,809,204 | G/A | — | uncertain significance |
| rs929272954 | 11:64,809,278 | G/A | — | likely benign |
| rs566895621 | 11:64,809,317 | C/T | — | uncertain significance |
| rs943428576 | 11:64,809,329 | T/A | — | uncertain significance |
| rs2495389613 | 11:64,809,330 | A/G | — | uncertain significance |
| rs376396030 | 11:64,811,708 | G/T | — | uncertain significance |
| rs763382275 | 11:64,811,750 | T/C | — | uncertain significance |
| rs780947705 | 11:64,811,793 | G/T | — | uncertain significance |
| rs780267443 | 11:64,811,811 | G/A | — | uncertain significance |
| rs748178524 | 11:64,811,820 | G/A | — | uncertain significance |
| rs779798673 | 11:64,811,877 | A/G | — | likely benign |
| rs376933360 | 11:64,811,886 | G/A | — | uncertain significance |
| rs768572224 | 11:64,811,906 | G/A | — | uncertain significance |
| rs370141149 | 11:64,811,910 | G/A | — | uncertain significance |
| rs377304009 | 11:64,811,993 | C/T | — | uncertain significance |
| rs78191496 | 11:64,811,994 | G/T | — | uncertain significance |
| rs758781513 | 11:64,812,060 | G/A | — | uncertain significance |
| rs772956492 | 11:64,812,101 | G/A | — | uncertain significance |
| rs201048547 | 11:64,812,173 | A/G | — | likely benign |
| rs756285380 | 11:64,812,174 | C/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.