SCG3
secretogranin III
Summary
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Known Variants24 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs3764220 | 15:51,972,058 | A/G | upstream gene variant | — |
| rs16964465 | 15:51,972,347 | A/C | upstream gene variant | — |
| rs16964476 | 15:51,974,224 | A/G | intron variant | — |
| rs775365790 | 15:51,975,292 | A/G | — | uncertain significance |
| rs765208740 | 15:51,975,452 | A/G | — | uncertain significance |
| rs1567215110 | 15:51,975,523 | T/C | — | uncertain significance |
| rs35106685 | 15:51,975,546 | T/C | — | benign |
| rs1484515440 | 15:51,975,595 | G/C | — | uncertain significance |
| rs764247472 | 15:51,975,599 | C/G | — | uncertain significance |
| rs142789927 | 15:51,975,615 | G/A | — | likely benign |
| rs148522098 | 15:51,980,487 | G/A | — | uncertain significance |
| rs199663742 | 15:51,980,597 | C/T | — | uncertain significance |
| rs774789007 | 15:51,981,524 | A/G | — | uncertain significance |
| rs772007121 | 15:51,984,356 | A/G | — | uncertain significance |
| rs147938991 | 15:51,984,363 | T/A | — | uncertain significance |
| rs200729963 | 15:51,984,403 | T/G | — | uncertain significance |
| rs374011939 | 15:51,984,500 | A/G | — | uncertain significance |
| rs148842206 | 15:51,988,123 | T/C | — | uncertain significance |
| rs1429606138 | 15:51,988,156 | C/A | — | uncertain significance |
| rs764433799 | 15:51,991,546 | C/A | — | uncertain significance |
| rs373126465 | 15:51,993,310 | C/T | — | uncertain significance |
| rs751055852 | 15:51,993,323 | T/G | — | uncertain significance |
| rs2055337645 | 15:51,993,418 | G/A | — | uncertain significance |
| rs185714715 | 15:52,010,915 | A/G | downstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.