SCN2B

sodium voltage-gated channel beta subunit 2

Summary

The protein encoded by this gene is the beta 2 subunit of the type II voltage-gated sodium channel. The encoded protein is involved in cell-cell adhesion and cell migration. Defects in this gene can be a cause of Brugada Syndrome, atrial fibrillation, or sudden infant death syndrome. [provided by RefSeq, Jul 2015]

Known Variants179 total

rsidPosition (GRCh37)AllelesClassClinVar
rs819261411:118,037,564A/G—benign
rs77635027211:118,037,597A/C—uncertain significance
rs105246764611:118,037,606T/A—uncertain significance
rs20026410711:118,037,610C/T—conflicting classifications of pathogenicity
rs37140924511:118,037,611G/A—likely benign
rs76254663711:118,037,616C/G—uncertain significance
rs58777702311:118,037,618T/C—uncertain significance
rs75123071311:118,037,620C/T—likely benign
rs14424821411:118,037,621G/A—conflicting classifications of pathogenicity
rs102465495411:118,037,628C/T—uncertain significance
rs159144415511:118,037,634C/T—uncertain significance
rs20197171911:118,037,635G/A—likely benign
rs36924494311:118,037,638C/T—likely benign
rs14003426511:118,037,639G/A—likely benign
rs148532032911:118,037,652C/T—uncertain significance
rs121405500711:118,037,653C/T—likely benign
rs132681164111:118,037,656G/A—likely benign
rs249759874311:118,037,657G/C—uncertain significance
rs249759875911:118,037,662C/T—likely benign
rs76955483911:118,037,665G/A—likely benign
rs11535315911:118,037,672G/C—conflicting classifications of pathogenicity
rs124394012311:118,037,674G/T—uncertain significance
rs249759881411:118,037,675C/T—uncertain significance
rs213551751211:118,037,683C/T—likely benign
rs194838881811:118,037,687T/C—uncertain significance
rs133666203011:118,037,689T/C—likely benign
rs194838897811:118,037,695T/A—uncertain significance
rs75908447511:118,037,696C/G—uncertain significance
rs155510065411:118,037,697T/C—uncertain significance
rs118771159211:118,037,701C/G—likely benign
rs249759893011:118,037,703C/T—uncertain significance
rs75657353811:118,037,704A/G—likely benign
rs194838926811:118,037,711A/C—uncertain significance
rs249759895611:118,037,721G/A—likely benign
rs75764448511:118,037,727A/G—likely benign
rs249759896811:118,037,728G/C—uncertain significance
rs75844095611:118,037,739C/G—uncertain significance
rs194838971011:118,037,742G/A—likely benign
rs129136219811:118,037,743G/A—likely benign
rs20168506911:118,037,748C/A—uncertain significance
rs20070923811:118,037,752G/A—likely benign
rs14031486411:118,037,754C/T—likely benign
rs121745257811:118,037,755G/A—likely benign
rs92353917311:118,037,760C/T—uncertain significance
rs87920954611:118,037,765A/C—uncertain significance
rs77431727111:118,037,772C/T—uncertain significance
rs77747953211:118,037,773G/A—likely benign
rs76033379811:118,037,780G/A—likely benign
rs75338970611:118,037,789C/T—uncertain significance
rs37677805611:118,037,793C/T—uncertain significance
rs76570195511:118,037,798G/T—uncertain significance
rs108530709411:118,037,803T/G—uncertain significance
rs819261311:118,037,813G/T—benign
rs249759928311:118,037,816G/A—likely benign
rs5797310111:118,037,879G/A—likely benign
rs67003811:118,037,931G/A—benign
rs7803896211:118,037,952C/A—likely benign
rs207564711:118,037,964G/C—benign
rs66187711:118,037,968C/T—benign
rs64844911:118,038,652G/A—benign
rs64838911:118,038,697T/C—benign
rs64797511:118,038,741C/T—benign
rs20173423711:118,038,787C/T—likely benign
rs194839926811:118,038,794C/G—uncertain significance
rs249760059611:118,038,802T/C—uncertain significance
rs117093323011:118,038,812C/T—uncertain significance
rs37137539211:118,038,814T/C—likely benign
rs124864647511:118,038,828G/A—uncertain significance
rs119303614211:118,038,829C/T—uncertain significance
rs194839983211:118,038,836C/T—uncertain significance
rs87885471211:118,038,838C/T—uncertain significance
rs78013812211:118,038,840G/A—likely benign
rs135717943711:118,038,843G/A—likely benign
rs37051457511:118,038,844C/T—uncertain significance
rs77617157511:118,038,852G/A—likely benign
rs124031670311:118,038,854G/T—uncertain significance
rs118702362611:118,038,859A/G—uncertain significance
rs131602332211:118,038,860T/A—uncertain significance
rs194840046811:118,038,863T/A—uncertain significance
rs249760071611:118,038,872T/C—uncertain significance
rs76329813511:118,038,879C/G—likely benign
rs100378148811:118,038,881C/T—uncertain significance
rs75203674111:118,038,888C/T—likely benign
rs14916924411:118,038,891C/T—likely benign
rs76758974011:118,038,892G/A—likely benign
rs75286333111:118,038,894C/T—likely benign
rs75475506211:118,038,899C/T—uncertain significance
rs7254414411:118,038,900G/A—likely benign
rs249760077611:118,038,902T/C—uncertain significance
rs75031344611:118,038,904C/T—uncertain significance
rs75823868211:118,038,905T/C—conflicting classifications of pathogenicity
rs96138047511:118,038,908G/A—likely benign
rs36798111611:118,038,910A/G—conflicting classifications of pathogenicity
rs86879305911:118,038,916G/A—uncertain significance
rs77652866811:118,038,921A/G—likely benign
rs78069508811:118,038,923C/T—uncertain significance
rs98115159311:118,038,924G/A—likely benign
rs144496808611:118,038,927C/T—likely benign
rs249760086311:118,038,945G/C—uncertain significance
rs55242196311:118,038,949T/C—uncertain significance

Showing 100 of 179 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.