SCN9A

sodium voltage-gated channel alpha subunit 9

Summary

This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder. [provided by RefSeq, Aug 2009]

Known Variants2,151 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs186838828	2:167,051,756	T/A	—	conflicting classifications of pathogenicity
rs191667986	2:167,051,865	T/C	—	likely benign
rs139483482	2:167,051,900	T/G	—	uncertain significance
rs201300071	2:167,051,978	C/T	—	uncertain significance
rs1015184575	2:167,051,980	A/G	—	uncertain significance
rs182687583	2:167,052,080	G/A	—	conflicting classifications of pathogenicity
rs1433503694	2:167,052,088	T/C	—	uncertain significance
rs199656729	2:167,052,129	C/T	—	uncertain significance
rs115766730	2:167,052,144	A/G	—	likely benign
rs201730339	2:167,052,196	A/C	—	uncertain significance
rs1693226507	2:167,052,237	G/T	—	uncertain significance
rs199559478	2:167,052,254	C/T	—	uncertain significance
rs200963393	2:167,052,322	G/A	—	uncertain significance
rs73017538	2:167,052,328	A/G	—	benign
rs1313840276	2:167,052,453	G/T	—	uncertain significance
rs199595958	2:167,052,461	G/C	—	likely benign
rs1472041217	2:167,052,505	A/G	—	uncertain significance
rs149873320	2:167,052,520	C/T	—	likely benign
rs13396526	2:167,052,542	C/T	—	benign
rs58249489	2:167,052,642	G/A	—	benign
rs200962814	2:167,052,838	G/A	—	conflicting classifications of pathogenicity
rs142172527	2:167,052,859	C/A	—	likely benign
rs185580193	2:167,052,870	T/A	—	likely benign
rs75345520	2:167,052,885	T/A	—	benign
rs200790957	2:167,052,954	C/A	—	conflicting classifications of pathogenicity
rs141310425	2:167,052,956	A/C	—	conflicting classifications of pathogenicity
rs199958892	2:167,052,960	A/G	—	uncertain significance
rs200750861	2:167,052,970	A/G	—	likely benign
rs201184093	2:167,052,991	C/T	—	conflicting classifications of pathogenicity
rs77565541	2:167,053,027	C/T	—	likely benign
rs17804037	2:167,053,028	G/C	—	benign
rs1062844	2:167,053,036	C/G	—	benign
rs77050817	2:167,053,046	G/C	—	benign
rs548072061	2:167,053,104	G/A	—	conflicting classifications of pathogenicity
rs202203220	2:167,053,367	A/G	—	uncertain significance
rs16851751	2:167,053,386	G/A	—	benign
rs114843828	2:167,053,408	C/T	—	benign
rs200353065	2:167,053,412	T/G	—	uncertain significance
rs1693263246	2:167,053,447	G/T	—	uncertain significance
rs16851753	2:167,053,522	C/T	—	benign
rs1693265771	2:167,053,539	A/G	—	uncertain significance
rs199848927	2:167,053,577	A/G	—	uncertain significance
rs73017542	2:167,053,690	G/C	—	benign
rs1693272137	2:167,053,760	A/G	—	uncertain significance
rs201120940	2:167,053,765	T/C	—	uncertain significance
rs896976419	2:167,053,799	C/A	—	uncertain significance
rs200338267	2:167,053,825	G/A	—	uncertain significance
rs11902920	2:167,053,998	A/C	—	benign
rs200393413	2:167,054,168	C/T	—	conflicting classifications of pathogenicity
rs16851754	2:167,054,169	G/A	—	benign
rs143727895	2:167,054,224	G/A	—	likely benign
rs201415802	2:167,054,234	C/T	—	uncertain significance
rs201424899	2:167,054,262	A/T	—	likely benign
rs200829562	2:167,054,282	A/G	—	uncertain significance
rs200611007	2:167,054,295	A/G	—	uncertain significance
rs199955941	2:167,054,347	G/T	—	uncertain significance
rs181229506	2:167,054,397	G/A	—	conflicting classifications of pathogenicity
rs538508619	2:167,054,513	T/C	—	conflicting classifications of pathogenicity
rs200153085	2:167,054,772	T/A	—	uncertain significance
rs201291538	2:167,054,774	T/C	—	uncertain significance
rs115464654	2:167,054,805	G/C	—	likely benign
rs185832567	2:167,054,820	G/A	—	likely benign
rs16851755	2:167,054,945	G/A	—	uncertain significance
rs140553451	2:167,054,947	G/A	—	likely benign
rs886055048	2:167,054,956	T/G	—	uncertain significance
rs200625860	2:167,054,965	C/T	—	conflicting classifications of pathogenicity
rs111510277	2:167,054,978	C/T	—	likely benign
rs1158330162	2:167,055,018	C/T	—	uncertain significance
rs201133173	2:167,055,023	A/G	—	uncertain significance
rs16851759	2:167,055,053	G/A	—	benign
rs200465050	2:167,055,057	G/A	—	likely benign
rs201137748	2:167,055,058	T/C	—	conflicting classifications of pathogenicity
rs150401869	2:167,055,164	T/C	—	likely benign
rs755454879	2:167,055,185	T/G	—	uncertain significance
rs780795130	2:167,055,186	T/A	—	uncertain significance
rs200785571	2:167,055,193	T/C	—	uncertain significance
rs755850299	2:167,055,195	T/C	—	uncertain significance
rs777230063	2:167,055,196	C/T	—	uncertain significance
rs201640210	2:167,055,200	G/C	—	conflicting classifications of pathogenicity
rs770802841	2:167,055,201	C/A	—	uncertain significance
rs199822303	2:167,055,204	T/A	—	conflicting classifications of pathogenicity
rs2106335469	2:167,055,206	T/A	—	uncertain significance
rs1693321468	2:167,055,210	C/T	—	uncertain significance
rs1553472666	2:167,055,220	C/T	—	uncertain significance
rs200744402	2:167,055,221	C/T	—	likely benign
rs1034452097	2:167,055,223	T/C	—	uncertain significance
rs1693322530	2:167,055,226	C/G	—	uncertain significance
rs1693322753	2:167,055,228	G/A	—	uncertain significance
rs771903438	2:167,055,231	C/G	—	uncertain significance
rs1553472676	2:167,055,232	T/C	—	uncertain significance
rs1553472678	2:167,055,233	G/A	—	likely benign
rs2106335560	2:167,055,234	T/C	—	uncertain significance
rs1693323281	2:167,055,235	C/T	—	uncertain significance
rs2106335577	2:167,055,239	T/A	—	uncertain significance
rs776830048	2:167,055,242	A/G	—	likely benign
rs761742207	2:167,055,243	T/C	—	uncertain significance
rs1378635410	2:167,055,244	A/G	—	uncertain significance
rs1164464636	2:167,055,248	C/G	—	uncertain significance
rs1553472700	2:167,055,250	C/A	—	uncertain significance
rs2468873605	2:167,055,255	T/A	—	uncertain significance

Showing 100 of 2,151 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.