SLA
Src like adaptor
Summary
Predicted to enable epidermal growth factor receptor binding activity and phosphotyrosine residue binding activity. Predicted to be involved in regulation of MAPK cascade and signal transduction. Predicted to be located in cytosol. Predicted to be part of COP9 signalosome. Predicted to be active in cytoplasm; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants33 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs765314621 | 8:134,050,806 | C/T | — | uncertain significance |
| rs200951688 | 8:134,050,854 | C/T | — | uncertain significance |
| rs1837541912 | 8:134,050,900 | C/T | — | uncertain significance |
| rs756835209 | 8:134,050,911 | C/T | — | uncertain significance |
| rs200563412 | 8:134,050,936 | C/T | — | uncertain significance |
| rs1407337918 | 8:134,052,351 | A/C | — | uncertain significance |
| rs2537001394 | 8:134,052,354 | C/T | — | uncertain significance |
| rs767704779 | 8:134,060,161 | A/G | — | uncertain significance |
| rs2687836 | 8:134,062,266 | A/T | — | — |
| rs201581025 | 8:134,063,091 | C/T | — | uncertain significance |
| rs772751614 | 8:134,063,092 | G/A | — | uncertain significance |
| rs1299842690 | 8:134,063,104 | G/A | — | uncertain significance |
| rs766029140 | 8:134,063,120 | C/T | — | likely benign |
| rs148579032 | 8:134,063,149 | C/T | — | uncertain significance |
| rs756605930 | 8:134,063,153 | A/T | — | likely benign |
| rs140451912 | 8:134,063,329 | G/T | intron variant | — |
| rs768169734 | 8:134,065,122 | C/T | — | — |
| rs188255084 | 8:134,067,653 | G/A | intron variant | — |
| rs2741200 | 8:134,071,833 | T/C | intron variant | — |
| rs756876988 | 8:134,072,352 | G/T | — | uncertain significance |
| rs760844853 | 8:134,072,425 | G/A | — | uncertain significance |
| rs562377138 | 8:134,072,465 | C/T | — | uncertain significance |
| rs771080149 | 8:134,072,480 | G/A | — | likely benign |
| rs372262693 | 8:134,081,744 | C/T | — | — |
| rs10113099 | 8:134,084,948 | A/T | intron variant | — |
| rs2739156 | 8:134,086,865 | T/C | — | — |
| rs7845804 | 8:134,089,676 | T/C | intron variant | — |
| rs183377267 | 8:134,098,696 | C/G | regulatory region variant | — |
| rs188028674 | 8:134,100,486 | C/G | intron variant | — |
| rs17703832 | 8:134,106,047 | G/A | intron variant | — |
| rs7013643 | 8:134,106,507 | T/C | intron variant | — |
| rs1000263 | 8:134,109,776 | C/G | intron variant | — |
| rs186646388 | 8:134,114,798 | G/A | — | likely benign |
Gene information from NCBI Gene. Variant classifications from ClinVar.