SLC22A16
solute carrier family 22 member 16
Summary
This gene encodes a member of the organic zwitterion transporter protein family which transports carnitine. The encoded protein has also been shown to transport anticancer drugs like bleomycin (PMID: 20037140) successful treatment has been correlated with the level of activity of this transporter in tumor cells. [provided by RefSeq, Dec 2011]
Known Variants41 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs770486939 | 6:110,746,110 | G/A | — | likely benign |
| rs556945678 | 6:110,746,141 | T/C | — | uncertain significance |
| rs941093143 | 6:110,746,167 | C/T | — | uncertain significance |
| rs1266718486 | 6:110,746,259 | A/C | — | uncertain significance |
| rs1774487289 | 6:110,752,415 | A/G | — | uncertain significance |
| rs201591965 | 6:110,752,417 | G/A | — | uncertain significance |
| rs1418268498 | 6:110,752,439 | G/A | — | uncertain significance |
| rs752227798 | 6:110,752,441 | C/A | — | uncertain significance |
| rs780334539 | 6:110,752,466 | C/T | — | uncertain significance |
| rs557232227 | 6:110,757,113 | C/T | — | uncertain significance |
| rs374614775 | 6:110,757,130 | A/C | — | uncertain significance |
| rs139688953 | 6:110,757,132 | C/T | — | uncertain significance |
| rs75035916 | 6:110,759,940 | C/T | — | benign |
| rs144862556 | 6:110,760,012 | C/G | — | uncertain significance |
| rs138778148 | 6:110,763,450 | G/C | — | uncertain significance |
| rs550927696 | 6:110,763,461 | T/C | — | uncertain significance |
| rs146182949 | 6:110,763,472 | A/C | — | uncertain significance |
| rs147996400 | 6:110,763,492 | A/G | — | uncertain significance |
| rs2534890980 | 6:110,763,617 | G/A | — | uncertain significance |
| rs1386742774 | 6:110,763,618 | G/A | — | uncertain significance |
| rs546437058 | 6:110,763,657 | G/T | — | uncertain significance |
| rs557250493 | 6:110,763,698 | A/G | — | uncertain significance |
| rs142910035 | 6:110,763,742 | G/C | — | benign |
| rs766536760 | 6:110,763,772 | C/G | — | uncertain significance |
| rs775327866 | 6:110,763,813 | T/A | — | uncertain significance |
| rs376231006 | 6:110,763,906 | C/T | — | uncertain significance |
| rs767022950 | 6:110,768,095 | G/C | — | uncertain significance |
| rs778848700 | 6:110,768,131 | G/T | — | uncertain significance |
| rs200912579 | 6:110,768,152 | A/T | — | uncertain significance |
| rs145601305 | 6:110,768,186 | G/T | — | uncertain significance |
| rs12194000 | 6:110,776,012 | A/G | intron variant | — |
| rs372140051 | 6:110,777,768 | G/A | — | uncertain significance |
| rs200786259 | 6:110,777,829 | C/G | — | uncertain significance |
| rs767582816 | 6:110,777,877 | G/C | — | uncertain significance |
| rs574205865 | 6:110,777,878 | G/C | — | uncertain significance |
| rs201509485 | 6:110,777,945 | G/A | — | uncertain significance |
| rs1445100058 | 6:110,777,960 | T/C | — | likely benign |
| rs750485928 | 6:110,777,961 | T/C | — | uncertain significance |
| rs6907567 | 6:110,777,962 | A/G | synonymous variant | — |
| rs714368 | 6:110,778,128 | T/G | missense variant | — |
| rs544817471 | 6:110,797,751 | A/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.