SLC26A8

solute carrier family 26 member 8

Summary

This gene encodes a member of the SLC26 gene family of anion transporters. Family members are well conserved in gene structure and protein length yet have markedly different tissue expression patterns. The expression of this gene appears to be restricted to spermatocytes. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2010]

Known Variants97 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs191020229	6:35,911,696	T/C	—	likely benign
rs398123027	6:35,911,730	G/A	missense variant	uncertain significance
rs1042278018	6:35,911,760	G/T	—	uncertain significance
rs764760105	6:35,911,770	C/G	—	uncertain significance
rs200359080	6:35,911,789	G/A	—	uncertain significance
rs61741366	6:35,911,856	A/G	—	benign
rs762591175	6:35,911,909	G/A	—	uncertain significance
rs138910476	6:35,911,951	C/T	—	likely benign
rs1485604306	6:35,911,977	C/G	—	likely benign
rs2534685883	6:35,912,043	C/A	—	uncertain significance
rs147340546	6:35,912,072	G/T	—	uncertain significance
rs773299771	6:35,912,095	A/G	—	uncertain significance
rs568128778	6:35,912,102	A/G	—	likely benign
rs7746080	6:35,912,269	A/G	—	benign
rs79380949	6:35,915,132	C/G	intron variant	—
rs144964138	6:35,915,192	G/C	intron variant	—
rs116200048	6:35,918,965	C/T	—	benign
rs142724470	6:35,918,978	C/T	missense variant	pathogenic
rs114153657	6:35,918,987	C/T	—	benign
rs115071158	6:35,919,038	C/T	—	uncertain significance
rs568126801	6:35,919,255	C/T	—	uncertain significance
rs375415581	6:35,919,266	G/C	—	uncertain significance
rs79271725	6:35,922,419	C/G	intron variant	—
rs138344479	6:35,922,961	C/G	—	uncertain significance
rs2534728243	6:35,923,002	C/T	—	uncertain significance
rs1333644820	6:35,923,074	C/T	—	uncertain significance
rs1217859361	6:35,923,110	C/G	—	uncertain significance
rs1772017796	6:35,923,129	C/T	—	uncertain significance
rs758016136	6:35,923,130	A/C	—	uncertain significance
rs143407739	6:35,923,133	C/G	—	uncertain significance
rs1198784390	6:35,923,210	T/C	—	uncertain significance
rs2295852	6:35,923,246	T/C	—	benign
rs375526103	6:35,923,255	C/T	—	uncertain significance
rs114646309	6:35,923,259	G/A	—	benign
rs149456040	6:35,927,247	G/A	—	uncertain significance
rs750925624	6:35,927,290	C/T	—	uncertain significance
rs376774482	6:35,927,292	C/T	—	likely benign
rs75822578	6:35,927,367	A/G	—	benign
rs60714103	6:35,927,483	G/C	—	benign
rs754385740	6:35,927,550	A/T	—	uncertain significance
rs1163172753	6:35,927,581	G/C	—	uncertain significance
rs12201122	6:35,927,778	C/T	—	benign
rs189215284	6:35,928,446	A/T	—	—
rs571951265	6:35,928,779	C/T	—	uncertain significance
rs753660355	6:35,928,791	A/C	—	uncertain significance
rs116528901	6:35,928,846	T/C	—	likely benign
rs776073302	6:35,928,854	G/A	—	likely benign
rs1294272370	6:35,930,347	T/C	—	uncertain significance
rs528129103	6:35,933,473	A/G	—	—
rs552101740	6:35,936,553	G/C	—	—
rs1189990531	6:35,936,656	T/C	—	uncertain significance
rs540188223	6:35,939,506	A/C	—	—
rs368170044	6:35,943,235	C/T	—	conflicting classifications of pathogenicity
rs77820058	6:35,943,269	T/C	—	benign
rs1343406335	6:35,944,991	T/C	—	uncertain significance
rs563497493	6:35,945,037	T/C	—	uncertain significance
rs9470185	6:35,945,343	C/T	—	benign
rs779208405	6:35,949,908	T/A	—	uncertain significance
rs9470186	6:35,950,075	G/C	—	benign
rs9470187	6:35,950,210	C/T	—	benign
rs138182405	6:35,953,125	C/T	downstream gene variant	—
rs6457870	6:35,959,161	G/A	—	benign
rs6457871	6:35,959,218	T/G	—	benign
rs1761164327	6:35,959,449	A/T	—	uncertain significance
rs766309755	6:35,959,474	T/G	—	uncertain significance
rs1387517749	6:35,959,541	G/T	—	likely benign
rs768954684	6:35,959,551	G/A	—	uncertain significance
rs546689610	6:35,960,307	C/T	—	uncertain significance
rs766444706	6:35,960,363	T/C	—	uncertain significance
rs17707331	6:35,960,390	C/T	—	benign
rs148004355	6:35,960,411	T/C	—	uncertain significance
rs768434254	6:35,960,436	A/G	—	likely benign
rs760904652	6:35,960,440	G/A	—	likely benign
rs10947584	6:35,960,614	C/T	—	benign
rs6908480	6:35,965,210	C/T	—	benign
rs79881330	6:35,965,365	C/T	—	benign
rs116074606	6:35,965,587	G/A	—	benign
rs757546070	6:35,965,610	C/T	—	likely benign
rs3800369	6:35,965,810	T/C	—	benign
rs17656461	6:35,965,869	T/A	—	benign
rs17713154	6:35,967,772	T/C	—	benign
rs952662385	6:35,967,811	C/T	—	uncertain significance
rs768118883	6:35,967,835	C/T	—	uncertain significance
rs142275991	6:35,967,836	G/A	—	likely benign
rs9462151	6:35,968,100	T/C	—	benign
rs140674756	6:35,968,600	T/C	intron variant	—
rs1220970427	6:35,980,048	A/G	—	pathogenic
rs72923104	6:35,980,053	G/A	—	likely benign
rs140210148	6:35,980,078	C/T	missense variant	pathogenic
rs748298266	6:35,980,083	C/G	—	uncertain significance
rs743923	6:35,980,121	T/C	—	benign
rs116146081	6:35,980,126	C/A	—	uncertain significance
rs851035	6:35,987,222	A/G	—	benign
rs1029670131	6:35,987,307	C/T	—	uncertain significance
rs61743377	6:35,987,425	T/C	—	benign
rs189677862	6:35,987,463	C/T	—	uncertain significance
rs851034	6:35,987,645	C/T	—	benign

Gene information from NCBI Gene. Variant classifications from ClinVar.