SLC47A2
solute carrier family 47 member 2
Summary
This gene encodes a protein belonging to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Known Variants41 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs376316493 | 17:19,582,027 | G/A | — | uncertain significance |
| rs113657311 | 17:19,582,054 | G/A | — | uncertain significance |
| rs374301491 | 17:19,582,057 | G/A | — | likely benign |
| rs201870806 | 17:19,582,078 | C/T | — | uncertain significance |
| rs201004962 | 17:19,582,079 | G/A | — | uncertain significance |
| rs35526408 | 17:19,582,128 | G/A | — | likely benign |
| rs890426530 | 17:19,582,159 | A/C | — | uncertain significance |
| rs760298590 | 17:19,582,161 | G/C | — | uncertain significance |
| rs764964844 | 17:19,582,180 | T/G | — | uncertain significance |
| rs966852445 | 17:19,582,211 | C/G | — | uncertain significance |
| rs374248552 | 17:19,584,877 | G/A | — | uncertain significance |
| rs139110700 | 17:19,584,896 | G/T | — | uncertain significance |
| rs201704161 | 17:19,584,907 | A/T | — | uncertain significance |
| rs2544436525 | 17:19,584,949 | T/G | — | uncertain significance |
| rs143935395 | 17:19,605,921 | G/C | — | uncertain significance |
| rs2544501941 | 17:19,606,447 | C/T | — | uncertain significance |
| rs552694046 | 17:19,607,474 | G/C | — | uncertain significance |
| rs748044622 | 17:19,608,784 | C/A | — | uncertain significance |
| rs772143428 | 17:19,608,785 | C/A | — | uncertain significance |
| rs1167386700 | 17:19,610,011 | A/G | — | uncertain significance |
| rs150225670 | 17:19,610,041 | G/C | — | uncertain significance |
| rs1186777046 | 17:19,610,065 | C/T | — | uncertain significance |
| rs376518777 | 17:19,610,071 | C/A | — | uncertain significance |
| rs781705181 | 17:19,611,651 | T/C | — | uncertain significance |
| rs2544531995 | 17:19,611,720 | A/G | — | uncertain significance |
| rs1225669586 | 17:19,611,733 | C/A | — | uncertain significance |
| rs138969135 | 17:19,611,776 | C/T | — | benign |
| rs2544549040 | 17:19,616,027 | G/A | — | uncertain significance |
| rs2544549142 | 17:19,616,038 | A/G | — | uncertain significance |
| rs1053935001 | 17:19,617,207 | G/A | — | uncertain significance |
| rs755164804 | 17:19,617,255 | C/T | — | uncertain significance |
| rs111749498 | 17:19,618,007 | C/T | regulatory region variant | — |
| rs758696163 | 17:19,618,078 | C/T | — | likely benign |
| rs147661457 | 17:19,618,471 | G/T | — | uncertain significance |
| rs780833814 | 17:19,618,476 | C/T | — | uncertain significance |
| rs2544564364 | 17:19,618,490 | C/T | — | uncertain significance |
| rs12450979 | 17:19,619,053 | C/G | upstream gene variant | — |
| rs142327106 | 17:19,619,828 | C/T | — | uncertain significance |
| rs12943590 | 17:19,619,998 | G/A | regulatory region variant | — |
| rs7213030 | 17:19,622,305 | G/A | regulatory region variant | — |
| rs74667296 | 17:19,623,278 | C/T | coding sequence variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.