SLC51A
solute carrier family 51 member A
Summary
Predicted to enable protein heterodimerization activity; protein homodimerization activity; and transmembrane transporter activity. Involved in bile acid secretion. Located in basolateral plasma membrane. Implicated in progressive familial intrahepatic cholestasis. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants51 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs747550066 | 3:195,943,578 | G/A | — | likely benign |
| rs779143599 | 3:195,943,583 | G/A | — | likely benign |
| rs201745104 | 3:195,943,590 | C/T | — | likely benign |
| rs536787679 | 3:195,943,591 | C/G | — | uncertain significance |
| rs148913870 | 3:195,943,592 | G/A | — | likely benign |
| rs1723589393 | 3:195,943,598 | G/C | — | uncertain significance |
| rs199724731 | 3:195,944,752 | C/T | — | likely benign |
| rs34352044 | 3:195,944,764 | C/T | — | benign |
| rs370423851 | 3:195,944,798 | C/T | — | uncertain significance |
| rs538670663 | 3:195,953,828 | T/C | — | likely benign |
| rs374534021 | 3:195,953,832 | C/T | — | likely benign |
| rs770488941 | 3:195,953,836 | C/A | — | uncertain significance |
| rs140837522 | 3:195,953,837 | C/T | — | likely benign |
| rs145068718 | 3:195,953,840 | G/T | — | likely benign |
| rs1260763347 | 3:195,953,853 | C/A | — | likely benign |
| rs138726787 | 3:195,953,919 | G/A | — | uncertain significance |
| rs759853415 | 3:195,953,959 | G/C | — | uncertain significance |
| rs146940905 | 3:195,953,971 | G/C | — | uncertain significance |
| rs149437891 | 3:195,954,554 | G/C | — | likely benign |
| rs538770464 | 3:195,954,594 | A/T | — | uncertain significance |
| rs781144406 | 3:195,954,977 | C/T | — | likely benign |
| rs148131579 | 3:195,954,995 | C/T | — | likely benign |
| rs1233491609 | 3:195,954,996 | G/A | — | uncertain significance |
| rs141959809 | 3:195,955,043 | G/T | — | uncertain significance |
| rs146078515 | 3:195,955,060 | G/A | — | uncertain significance |
| rs143576972 | 3:195,955,084 | T/C | — | uncertain significance |
| rs777508608 | 3:195,955,129 | G/A | — | uncertain significance |
| rs779232895 | 3:195,955,670 | C/T | — | likely benign |
| rs1488534773 | 3:195,955,673 | C/T | — | likely benign |
| rs768221226 | 3:195,955,701 | G/C | — | uncertain significance |
| rs1388285232 | 3:195,955,714 | C/T | — | pathogenic |
| rs139191241 | 3:195,955,720 | G/A | — | uncertain significance |
| rs145114474 | 3:195,955,744 | C/G | — | uncertain significance |
| rs780006859 | 3:195,955,761 | C/T | — | likely benign |
| rs939885 | 3:195,955,762 | A/G | — | benign |
| rs144417558 | 3:195,955,767 | C/T | — | likely benign |
| rs192475271 | 3:195,955,799 | G/A | — | likely benign |
| rs376473125 | 3:195,956,778 | G/T | — | likely benign |
| rs2474005278 | 3:195,956,807 | C/T | — | likely benign |
| rs759366337 | 3:195,956,823 | T/G | — | uncertain significance |
| rs17852687 | 3:195,956,827 | T/C | — | benign |
| rs9849888 | 3:195,956,874 | G/A | — | likely benign |
| rs372259930 | 3:195,956,893 | G/A | — | likely benign |
| rs202017943 | 3:195,956,909 | G/C | — | likely benign |
| rs372691007 | 3:195,959,285 | C/T | — | likely benign |
| rs140725914 | 3:195,959,323 | A/G | — | uncertain significance |
| rs202152149 | 3:195,959,341 | A/G | — | uncertain significance |
| rs963667914 | 3:195,959,348 | G/A | — | uncertain significance |
| rs1476331 | 3:195,959,924 | T/C | — | benign |
| rs530565206 | 3:195,959,951 | C/T | — | likely benign |
| rs775239578 | 3:195,960,059 | C/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.