SLC5A10
solute carrier family 5 member 10
Summary
This gene is a member of the sodium/glucose transporter family. Members of this family are sodium-dependent transporters and can be divided into two subfamilies based on sequence homology, one that co-transports sugars and the second that transports molecules such as ascorbate, choline, iodide, lipoate, monocaroboxylates, and pantothenate. The protein encoded by this gene has the highest affinity for mannose and has been reported to be most highly expressed in the kidney. This protein may function as a kidney-specific, sodium-dependent mannose and fructose co-transporter. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
Known Variants47 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs757159430 | 17:18,855,555 | G/A | — | uncertain significance |
| rs372402739 | 17:18,855,570 | G/A | — | uncertain significance |
| rs200855886 | 17:18,862,004 | C/T | — | uncertain significance |
| rs754577623 | 17:18,862,010 | A/G | — | uncertain significance |
| rs201995487 | 17:18,862,020 | C/T | — | uncertain significance |
| rs776940039 | 17:18,862,047 | G/A | — | uncertain significance |
| rs759445784 | 17:18,862,460 | C/T | — | uncertain significance |
| rs201103784 | 17:18,862,466 | G/T | — | uncertain significance |
| rs376732499 | 17:18,862,514 | G/A | — | uncertain significance |
| rs141133983 | 17:18,862,536 | C/T | — | uncertain significance |
| rs146918144 | 17:18,862,543 | C/A | — | uncertain significance |
| rs375378878 | 17:18,862,926 | G/A | — | uncertain significance |
| rs547915569 | 17:18,863,913 | G/T | — | uncertain significance |
| rs906367161 | 17:18,872,365 | C/A | — | uncertain significance |
| rs2544643578 | 17:18,872,670 | T/C | — | uncertain significance |
| rs780644827 | 17:18,872,706 | T/C | — | uncertain significance |
| rs371624697 | 17:18,872,715 | C/T | — | uncertain significance |
| rs201487616 | 17:18,874,435 | G/A | — | uncertain significance |
| rs1479130654 | 17:18,874,438 | C/G | — | uncertain significance |
| rs769492030 | 17:18,874,439 | A/G | — | uncertain significance |
| rs199714461 | 17:18,874,455 | A/G | — | uncertain significance |
| rs571295774 | 17:18,874,517 | T/C | — | uncertain significance |
| rs750073061 | 17:18,880,194 | C/T | — | uncertain significance |
| rs202168324 | 17:18,880,287 | C/T | — | uncertain significance |
| rs1318455835 | 17:18,916,759 | G/A | — | uncertain significance |
| rs141223606 | 17:18,918,367 | C/T | — | uncertain significance |
| rs768817506 | 17:18,918,487 | G/A | — | uncertain significance |
| rs1337481087 | 17:18,918,500 | T/G | — | uncertain significance |
| rs1345066540 | 17:18,918,503 | T/C | — | uncertain significance |
| rs771322586 | 17:18,918,511 | C/T | — | uncertain significance |
| rs200567946 | 17:18,922,761 | G/A | — | uncertain significance |
| rs114835363 | 17:18,922,851 | C/T | — | uncertain significance |
| rs899058280 | 17:18,922,873 | T/C | — | uncertain significance |
| rs762789917 | 17:18,922,888 | G/A | — | likely benign |
| rs1473977230 | 17:18,922,897 | A/G | — | uncertain significance |
| rs1453244081 | 17:18,922,899 | G/C | — | uncertain significance |
| rs2544787959 | 17:18,923,026 | G/A | — | uncertain significance |
| rs61741107 | 17:18,923,027 | G/A | missense variant | — |
| rs2044222158 | 17:18,923,066 | C/T | — | uncertain significance |
| rs757721848 | 17:18,923,069 | C/T | — | uncertain significance |
| rs2544788313 | 17:18,923,086 | T/C | — | uncertain significance |
| rs144459798 | 17:18,923,099 | C/T | — | uncertain significance |
| rs770766684 | 17:18,923,125 | C/T | — | uncertain significance |
| rs1241991685 | 17:18,923,508 | C/G | — | uncertain significance |
| rs753670509 | 17:18,923,643 | G/A | — | uncertain significance |
| rs777936836 | 17:18,923,668 | T/G | — | uncertain significance |
| rs1037885740 | 17:18,923,707 | T/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.