SYT10
synaptotagmin 10
Summary
Predicted to enable several functions, including calcium ion binding activity; calcium ion sensor activity; and calcium-dependent phospholipid binding activity. Predicted to be involved in positive regulation of calcium ion-dependent exocytosis; presynaptic dense core vesicle exocytosis; and sensory perception of smell. Predicted to be located in transport vesicle membrane. Predicted to be active in several cellular components, including exocytic vesicle; glutamatergic synapse; and presynapse. [provided by Alliance of Genome Resources, Apr 2025]
Known Variants37 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs201820175 | 12:33,529,782 | G/T | — | uncertain significance |
| rs200421519 | 12:33,529,788 | G/C | — | uncertain significance |
| rs34361405 | 12:33,529,823 | G/A | — | benign |
| rs2497874069 | 12:33,532,844 | C/T | — | uncertain significance |
| rs376432626 | 12:33,532,847 | C/T | — | uncertain significance |
| rs2497874208 | 12:33,532,892 | C/T | — | uncertain significance |
| rs764585701 | 12:33,535,286 | A/G | — | likely benign |
| rs35190376 | 12:33,535,395 | G/C | — | conflicting classifications of pathogenicity |
| rs1251003302 | 12:33,535,422 | C/T | — | uncertain significance |
| rs992096708 | 12:33,535,424 | T/G | — | uncertain significance |
| rs1462537639 | 12:33,535,444 | T/C | — | uncertain significance |
| rs149372161 | 12:33,538,129 | G/A | — | uncertain significance |
| rs771669390 | 12:33,538,225 | T/C | — | uncertain significance |
| rs7315695 | 12:33,551,841 | G/T | — | — |
| rs769167593 | 12:33,559,942 | C/T | — | uncertain significance |
| rs541132224 | 12:33,559,945 | G/T | — | uncertain significance |
| rs2497904008 | 12:33,559,959 | T/G | — | uncertain significance |
| rs1866360482 | 12:33,559,969 | C/A | — | uncertain significance |
| rs2497904469 | 12:33,560,099 | T/G | — | uncertain significance |
| rs757393799 | 12:33,560,273 | T/A | — | uncertain significance |
| rs7980799 | 12:33,576,990 | A/C | intron variant | — |
| rs2497921001 | 12:33,579,080 | A/T | — | uncertain significance |
| rs754021131 | 12:33,579,121 | T/C | — | uncertain significance |
| rs2138432701 | 12:33,579,196 | G/C | — | uncertain significance |
| rs780151495 | 12:33,579,206 | C/T | — | uncertain significance |
| rs11832759 | 12:33,579,213 | G/A | — | benign |
| rs142035623 | 12:33,579,243 | T/G | — | uncertain significance |
| rs377068491 | 12:33,579,298 | G/A | — | uncertain significance |
| rs759681647 | 12:33,579,342 | A/C | — | uncertain significance |
| rs2497921382 | 12:33,579,353 | A/G | — | uncertain significance |
| rs778562353 | 12:33,579,396 | G/T | — | uncertain significance |
| rs771869540 | 12:33,579,404 | C/T | — | uncertain significance |
| rs777113468 | 12:33,592,312 | C/A | — | uncertain significance |
| rs750439224 | 12:33,592,381 | G/A | — | uncertain significance |
| rs367918971 | 12:33,592,384 | A/C | — | uncertain significance |
| rs550901250 | 12:33,592,421 | A/T | — | uncertain significance |
| rs756517811 | 12:33,592,424 | G/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.