SYT7
synaptotagmin 7
Summary
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Known Variants34 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs138241672 | 11:61,283,135 | T/C | downstream gene variant | — |
| rs530561334 | 11:61,283,815 | C/A | — | — |
| rs201342343 | 11:61,290,575 | T/C | — | likely benign |
| rs773908428 | 11:61,290,732 | C/A | — | uncertain significance |
| rs200881282 | 11:61,291,334 | C/T | — | uncertain significance |
| rs2540239546 | 11:61,291,380 | A/G | — | uncertain significance |
| rs367997522 | 11:61,291,409 | C/T | — | uncertain significance |
| rs2062448777 | 11:61,291,927 | G/A | — | uncertain significance |
| rs143559864 | 11:61,292,857 | C/T | intron variant | — |
| rs553474743 | 11:61,292,941 | C/T | — | — |
| rs753360206 | 11:61,295,486 | C/T | — | uncertain significance |
| rs764750362 | 11:61,295,550 | G/A | — | likely benign |
| rs374646904 | 11:61,295,611 | C/T | — | uncertain significance |
| rs2540279436 | 11:61,295,634 | A/C | — | uncertain significance |
| rs192017412 | 11:61,298,932 | G/C | — | — |
| rs2540325898 | 11:61,300,517 | C/T | — | uncertain significance |
| rs2540327443 | 11:61,300,585 | C/T | — | uncertain significance |
| rs146563315 | 11:61,309,911 | C/T | — | benign |
| rs150684478 | 11:61,312,726 | G/T | upstream gene variant | — |
| rs771842368 | 11:61,318,878 | G/A | — | uncertain significance |
| rs428619 | 11:61,319,111 | C/T | regulatory region variant | — |
| rs377288794 | 11:61,322,788 | C/T | — | — |
| rs746816972 | 11:61,323,605 | C/T | — | uncertain significance |
| rs144496851 | 11:61,323,611 | G/C | — | uncertain significance |
| rs142606373 | 11:61,323,614 | C/G | — | uncertain significance |
| rs147650793 | 11:61,323,662 | C/A | — | uncertain significance |
| rs11821795 | 11:61,326,009 | T/G | — | — |
| rs78765146 | 11:61,333,050 | A/C | intron variant | — |
| rs117145549 | 11:61,333,998 | G/A | intron variant | — |
| rs117227367 | 11:61,337,996 | G/A | intron variant | — |
| rs573116940 | 11:61,342,225 | G/A | — | — |
| rs999163469 | 11:61,348,285 | C/T | — | uncertain significance |
| rs544776242 | 11:61,349,057 | C/T | — | — |
| rs145471418 | 11:61,351,587 | C/T | upstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.