TAC1

tachykinin precursor 1

Summary

This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]

Known Variants6 total

rsidPosition (GRCh37)AllelesClassClinVar
rs2013823227:97,361,936C/Gbenign
rs14548708917:97,363,104T/Cuncertain significance
rs1420315577:97,365,615T/Clikely benign
rs7474440057:97,365,643G/Auncertain significance
rs781452577:97,366,332G/T
rs14612591157:97,369,208G/Auncertain significance

Gene information from NCBI Gene. Variant classifications from ClinVar.