TAF7
TATA-box binding protein associated factor 7
Summary
The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5. The protein encoded by this gene is a component of the TFIID protein complex, a complex which binds to the TATA box in class II promoters and recruits RNA polymerase II and other factors. This particular subunit interacts with the largest TFIID subunit, as well as multiple transcription activators. The protein is required for transcription by promoters targeted by RNA polymerase II. [provided by RefSeq, Jul 2008]
Known Variants20 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs756001505 | 5:140,698,568 | C/G | — | uncertain significance |
| rs376114900 | 5:140,698,651 | C/T | — | uncertain significance |
| rs775109056 | 5:140,698,693 | T/C | — | uncertain significance |
| rs2479607875 | 5:140,698,768 | G/T | — | uncertain significance |
| rs374515539 | 5:140,698,857 | T/A | — | uncertain significance |
| rs202078222 | 5:140,698,884 | T/C | — | uncertain significance |
| rs752777886 | 5:140,698,894 | C/T | — | uncertain significance |
| rs1458544356 | 5:140,698,975 | A/G | — | uncertain significance |
| rs774032064 | 5:140,699,005 | C/G | — | uncertain significance |
| rs2479608743 | 5:140,699,019 | T/C | — | uncertain significance |
| rs1387924419 | 5:140,699,086 | C/T | — | uncertain significance |
| rs372105449 | 5:140,699,216 | C/G | — | uncertain significance |
| rs770915401 | 5:140,699,224 | A/G | — | uncertain significance |
| rs755779347 | 5:140,699,343 | T/C | — | uncertain significance |
| rs778667242 | 5:140,699,404 | G/C | — | uncertain significance |
| rs1197056595 | 5:140,699,443 | T/C | — | uncertain significance |
| rs144765111 | 5:140,699,512 | A/C | — | uncertain significance |
| rs143483447 | 5:140,699,881 | G/C | coding sequence variant | — |
| rs140942166 | 5:140,700,309 | G/A | coding sequence variant | — |
| rs10875595 | 5:140,700,489 | T/G | regulatory region variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.