TAFA2
TAFA chemokine like family member 2
Summary
This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. [provided by RefSeq, Jul 2008]
Known Variants17 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs139053149 | 12:62,147,452 | T/C | — | uncertain significance |
| rs2540596889 | 12:62,148,738 | T/C | — | uncertain significance |
| rs2198776 | 12:62,234,833 | C/G | — | — |
| rs17605016 | 12:62,250,420 | T/G | intron variant | — |
| rs181558760 | 12:62,261,118 | C/A | — | uncertain significance |
| rs1166469649 | 12:62,261,155 | T/G | — | uncertain significance |
| rs2540689105 | 12:62,261,196 | C/T | — | uncertain significance |
| rs1031582 | 12:62,263,645 | A/T | — | — |
| rs4397906 | 12:62,264,391 | T/A | — | — |
| rs11174267 | 12:62,386,600 | A/G | intron variant | — |
| rs527569697 | 12:62,388,456 | A/G | — | — |
| rs535733797 | 12:62,466,314 | C/A | — | — |
| rs1146079 | 12:62,485,472 | C/A | — | — |
| rs10784285 | 12:62,558,314 | C/T | intron variant | — |
| rs10784289 | 12:62,606,931 | G/A | intron variant | — |
| rs11615916 | 12:62,610,860 | A/G | intron variant | — |
| rs11174399 | 12:62,646,556 | G/A | regulatory region variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.