TAOK1
TAO kinase 1
Summary
Enables alpha-tubulin binding activity; beta-tubulin binding activity; and kinase activity. Involved in several processes, including mitotic G2 DNA damage checkpoint signaling; negative regulation of microtubule depolymerization; and positive regulation of MAPK cascade. Located in several cellular components, including microtubule cytoskeleton; nuclear body; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants158 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs9915622 | 17:27,722,195 | G/T | — | — |
| rs145772295 | 17:27,726,131 | A/G | intron variant | — |
| rs9907984 | 17:27,726,151 | A/G | intron variant | — |
| rs565366829 | 17:27,726,486 | A/G | — | — |
| rs2320954 | 17:27,729,696 | G/A | intron variant | — |
| rs768073610 | 17:27,730,569 | T/G | — | — |
| rs7210867 | 17:27,737,776 | C/G | — | — |
| rs11871003 | 17:27,738,395 | C/T | — | — |
| rs183783019 | 17:27,750,003 | A/T | downstream gene variant | — |
| rs6505129 | 17:27,753,618 | G/C | — | — |
| rs145046282 | 17:27,753,930 | C/G | upstream gene variant | — |
| rs9900280 | 17:27,769,598 | G/A | downstream gene variant | — |
| rs138594590 | 17:27,778,596 | G/A | — | benign |
| rs56343780 | 17:27,778,623 | C/T | — | likely benign |
| rs7210399 | 17:27,780,216 | T/G | — | — |
| rs148379086 | 17:27,783,249 | C/T | intron variant | — |
| rs8065958 | 17:27,792,530 | T/G | — | — |
| rs2030687889 | 17:27,794,166 | C/T | — | pathogenic |
| rs1312821862 | 17:27,794,173 | T/C | — | uncertain significance |
| rs1379927018 | 17:27,794,175 | C/T | — | uncertain significance |
| rs1287976071 | 17:27,794,183 | T/G | — | uncertain significance |
| rs370714623 | 17:27,794,192 | G/A | — | likely benign |
| rs2153025663 | 17:27,794,193 | G/A | — | uncertain significance |
| rs1567726409 | 17:27,794,196 | A/T | — | uncertain significance |
| rs2153025665 | 17:27,794,199 | A/C | — | uncertain significance |
| rs533275090 | 17:27,794,235 | G/A | — | pathogenic |
| rs517967 | 17:27,794,988 | T/A | — | — |
| rs2508195100 | 17:27,802,686 | A/G | — | likely pathogenic |
| rs2153026442 | 17:27,802,693 | G/A | — | uncertain significance |
| rs2153026444 | 17:27,802,706 | A/G | — | uncertain significance |
| rs2508195156 | 17:27,802,710 | A/C | — | likely pathogenic |
| rs1200088142 | 17:27,802,716 | A/G | — | uncertain significance |
| rs2030928353 | 17:27,802,730 | A/G | — | uncertain significance |
| rs2508195356 | 17:27,802,772 | C/T | — | uncertain significance |
| rs147203802 | 17:27,802,783 | A/G | — | benign |
| rs2030976698 | 17:27,804,704 | C/T | — | likely pathogenic |
| rs2508199498 | 17:27,804,722 | A/G | — | uncertain significance |
| rs2508200760 | 17:27,805,295 | G/A | — | uncertain significance |
| rs2030989355 | 17:27,805,365 | G/T | — | likely pathogenic |
| rs2508205699 | 17:27,807,387 | G/A | — | likely pathogenic |
| rs56387760 | 17:27,807,416 | G/A | — | benign |
| rs2153026774 | 17:27,807,429 | G/A | — | uncertain significance |
| rs145506168 | 17:27,807,455 | T/C | — | likely benign |
| rs747156223 | 17:27,807,463 | C/T | — | uncertain significance |
| rs2031037130 | 17:27,807,478 | C/T | — | uncertain significance |
| rs2508206186 | 17:27,807,493 | C/T | — | conflicting classifications of pathogenicity |
| rs2153026918 | 17:27,809,240 | A/C | — | likely pathogenic |
| rs2153026921 | 17:27,809,270 | G/A | — | likely pathogenic |
| rs2153026922 | 17:27,809,271 | A/T | — | uncertain significance |
| rs2031080312 | 17:27,809,277 | G/A | — | pathogenic |
| rs2508210919 | 17:27,809,295 | G/A | — | uncertain significance |
| rs2508210940 | 17:27,809,304 | T/C | — | likely pathogenic |
| rs369402043 | 17:27,809,312 | C/T | — | likely benign |
| rs7216243 | 17:27,814,038 | G/T | — | — |
| rs559972 | 17:27,814,496 | C/T | intron variant | — |
| rs2508226327 | 17:27,816,684 | G/T | — | likely pathogenic |
| rs9897675 | 17:27,816,686 | A/G | — | benign |
| rs2153027505 | 17:27,816,717 | A/G | — | uncertain significance |
| rs2508226400 | 17:27,816,718 | T/A | — | likely pathogenic |
| rs2508226417 | 17:27,816,739 | C/A | — | uncertain significance |
| rs762098763 | 17:27,816,757 | C/T | — | uncertain significance |
| rs1197131858 | 17:27,816,773 | A/G | — | uncertain significance |
| rs377646005 | 17:27,816,779 | A/G | — | uncertain significance |
| rs2508226504 | 17:27,816,781 | T/C | — | uncertain significance |
| rs1002421158 | 17:27,818,816 | G/A | — | uncertain significance |
| rs1191085308 | 17:27,818,858 | G/C | — | likely pathogenic |
| rs2508230637 | 17:27,818,878 | T/G | — | uncertain significance |
| rs751852480 | 17:27,822,593 | C/T | — | likely benign |
| rs1488639246 | 17:27,822,599 | C/T | — | uncertain significance |
| rs143989572 | 17:27,822,600 | G/A | — | likely benign |
| rs2153027979 | 17:27,822,623 | C/G | — | uncertain significance |
| rs865873514 | 17:27,822,674 | C/T | — | pathogenic |
| rs759761132 | 17:27,822,704 | G/A | — | likely benign |
| rs533949 | 17:27,824,900 | G/C | intron variant | — |
| rs116616401 | 17:27,825,329 | C/T | — | benign |
| rs750735679 | 17:27,825,346 | A/T | — | uncertain significance |
| rs777374325 | 17:27,825,400 | C/T | — | uncertain significance |
| rs2508247153 | 17:27,825,437 | T/A | — | uncertain significance |
| rs368442296 | 17:27,825,479 | A/G | — | likely benign |
| rs567563190 | 17:27,826,462 | C/A | — | — |
| rs7216246 | 17:27,826,582 | C/G | — | — |
| rs140070219 | 17:27,828,256 | A/T | — | — |
| rs372629242 | 17:27,829,616 | A/T | — | uncertain significance |
| rs1365569773 | 17:27,829,659 | C/A | — | uncertain significance |
| rs762696676 | 17:27,829,683 | G/A | — | likely benign |
| rs2508257393 | 17:27,829,692 | C/T | — | uncertain significance |
| rs146410053 | 17:27,829,701 | G/A | — | likely benign |
| rs2153028697 | 17:27,829,706 | C/T | — | pathogenic |
| rs2153028699 | 17:27,829,727 | C/T | — | pathogenic |
| rs1360526974 | 17:27,834,946 | C/G | — | uncertain significance |
| rs2508268872 | 17:27,834,989 | C/T | — | pathogenic |
| rs781597072 | 17:27,835,052 | C/T | — | uncertain significance |
| rs508706 | 17:27,835,138 | C/T | — | benign |
| rs2508269341 | 17:27,835,151 | G/A | — | likely pathogenic |
| rs777328070 | 17:27,837,879 | T/C | — | likely benign |
| rs2508274424 | 17:27,837,905 | G/T | — | uncertain significance |
| rs2153029597 | 17:27,837,949 | T/C | — | pathogenic |
| rs2508290987 | 17:27,844,568 | C/A | — | uncertain significance |
| rs1026063439 | 17:27,844,579 | C/T | — | pathogenic |
| rs2031840733 | 17:27,844,583 | G/A | — | uncertain significance |
Showing 100 of 158 variants. Use the SNP search for the full list.
Gene information from NCBI Gene. Variant classifications from ClinVar.