TAS2R1
taste 2 receptor member 1
Summary
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. This intronless taste receptor gene encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is mapped to chromosome 5p15, the location of a genetic locus (PROP) that controls the detection of the bitter compound 6-n-propyl-2-thiouracil. [provided by RefSeq, Jul 2008]
Known Variants13 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs933530598 | 5:9,629,308 | T/A | — | uncertain significance |
| rs764018861 | 5:9,629,424 | A/C | — | uncertain significance |
| rs1739824602 | 5:9,629,526 | G/C | — | uncertain significance |
| rs372736864 | 5:9,629,528 | C/T | — | likely benign |
| rs2234232 | 5:9,629,723 | C/T | — | benign |
| rs139538133 | 5:9,629,844 | C/T | — | uncertain significance |
| rs370954622 | 5:9,629,906 | G/A | — | uncertain significance |
| rs149835603 | 5:9,629,965 | C/A | — | uncertain significance |
| rs1281787651 | 5:9,629,978 | A/T | — | uncertain significance |
| rs763312142 | 5:9,629,987 | A/T | — | uncertain significance |
| rs112065280 | 5:9,633,586 | T/A | — | — |
| rs7725217 | 5:9,756,329 | A/C | upstream gene variant | — |
| rs73039647 | 5:9,825,082 | C/T | intron variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.