TBC1D2
TBC1 domain family member 2
Summary
Enables GTPase activator activity and cadherin binding activity. Involved in positive regulation of GTPase activity. Located in several cellular components, including cytoplasmic vesicle; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants70 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs34769888 | 9:100,961,704 | C/T | — | benign |
| rs757114027 | 9:100,961,715 | C/T | — | uncertain significance |
| rs764982294 | 9:100,961,718 | C/T | — | uncertain significance |
| rs202075219 | 9:100,961,722 | G/A | — | likely benign |
| rs192033192 | 9:100,961,730 | C/T | — | uncertain significance |
| rs2490916278 | 9:100,961,745 | T/C | — | uncertain significance |
| rs61748711 | 9:100,961,769 | C/T | — | benign |
| rs1053262647 | 9:100,961,793 | C/T | — | uncertain significance |
| rs769298700 | 9:100,961,829 | C/T | — | uncertain significance |
| rs137868712 | 9:100,962,566 | G/A | — | likely benign |
| rs147981592 | 9:100,963,778 | G/A | — | benign |
| rs776900208 | 9:100,963,856 | C/T | — | likely benign |
| rs371626516 | 9:100,963,871 | C/T | — | uncertain significance |
| rs752444063 | 9:100,963,891 | G/T | — | uncertain significance |
| rs774546155 | 9:100,965,580 | G/T | — | uncertain significance |
| rs376426928 | 9:100,965,635 | G/C | — | uncertain significance |
| rs150780279 | 9:100,965,662 | C/G | — | uncertain significance |
| rs201501022 | 9:100,965,685 | G/A | — | uncertain significance |
| rs1722039456 | 9:100,970,995 | A/T | — | uncertain significance |
| rs1489779515 | 9:100,970,998 | G/A | — | uncertain significance |
| rs750718365 | 9:100,971,008 | C/G | — | uncertain significance |
| rs759255741 | 9:100,971,044 | A/C | — | uncertain significance |
| rs1768912660 | 9:100,971,184 | A/C | — | uncertain significance |
| rs377646274 | 9:100,971,202 | C/T | — | uncertain significance |
| rs914891511 | 9:100,971,203 | G/A | — | uncertain significance |
| rs200863836 | 9:100,971,217 | C/T | — | uncertain significance |
| rs761820400 | 9:100,971,232 | C/T | — | uncertain significance |
| rs767720149 | 9:100,971,251 | C/T | — | uncertain significance |
| rs768811594 | 9:100,971,392 | C/T | — | likely benign |
| rs371048416 | 9:100,973,032 | C/T | — | likely benign |
| rs61756693 | 9:100,973,036 | G/C | — | benign |
| rs1413875299 | 9:100,973,044 | C/A | — | uncertain significance |
| rs1028659023 | 9:100,973,087 | G/C | — | uncertain significance |
| rs150561627 | 9:100,973,115 | A/C | — | likely benign |
| rs746405499 | 9:100,973,118 | T/C | — | uncertain significance |
| rs530140181 | 9:100,974,620 | C/T | — | — |
| rs1000821216 | 9:100,975,423 | C/A | — | uncertain significance |
| rs1237925989 | 9:100,983,120 | G/T | — | uncertain significance |
| rs200005226 | 9:100,983,127 | T/C | — | likely benign |
| rs1020116518 | 9:100,983,158 | T/C | — | uncertain significance |
| rs967200270 | 9:100,983,168 | C/T | — | uncertain significance |
| rs143908614 | 9:100,983,215 | A/G | — | benign |
| rs146890718 | 9:100,983,229 | C/T | — | benign |
| rs2491001363 | 9:100,983,254 | T/C | — | uncertain significance |
| rs907466596 | 9:100,983,320 | G/T | — | uncertain significance |
| rs61753563 | 9:100,983,329 | G/A | — | benign |
| rs1379204966 | 9:100,983,342 | G/A | — | uncertain significance |
| rs903083472 | 9:100,983,368 | C/A | — | uncertain significance |
| rs374861819 | 9:100,983,381 | C/T | — | uncertain significance |
| rs778157051 | 9:100,991,260 | G/A | — | uncertain significance |
| rs538999044 | 9:100,991,263 | T/A | — | uncertain significance |
| rs757691025 | 9:100,991,355 | C/T | — | uncertain significance |
| rs139062706 | 9:100,991,356 | G/T | — | uncertain significance |
| rs548342801 | 9:100,995,710 | C/T | — | uncertain significance |
| rs139045055 | 9:100,995,812 | G/A | — | uncertain significance |
| rs1463593432 | 9:101,006,288 | C/T | — | uncertain significance |
| rs368737708 | 9:101,006,309 | T/C | — | uncertain significance |
| rs373090046 | 9:101,006,361 | G/T | — | likely benign |
| rs61753568 | 9:101,006,405 | T/C | — | uncertain significance |
| rs140114775 | 9:101,014,205 | C/T | — | uncertain significance |
| rs2491123914 | 9:101,017,477 | G/C | — | uncertain significance |
| rs778289499 | 9:101,017,537 | G/A | — | uncertain significance |
| rs759714625 | 9:101,017,582 | G/A | — | uncertain significance |
| rs372758153 | 9:101,017,608 | G/C | — | uncertain significance |
| rs115736722 | 9:101,017,677 | A/G | — | benign |
| rs369711045 | 9:101,017,691 | G/A | — | uncertain significance |
| rs150927921 | 9:101,017,735 | G/T | — | uncertain significance |
| rs199544260 | 9:101,017,736 | G/A | — | uncertain significance |
| rs2491125661 | 9:101,017,748 | G/T | — | uncertain significance |
| rs140786799 | 9:101,017,774 | C/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.