TMEM135
transmembrane protein 135
Summary
Predicted to enable lipid transporter activity. Predicted to be involved in several processes, including fatty acid derivative transport; fatty acid metabolic process; and long-chain fatty acid transport. Predicted to act upstream of or within several processes, including regulation of oxidative phosphorylation; response to food; and retinal pigment epithelium development. Predicted to be located in peroxisome. Predicted to be active in peroxisomal membrane. [provided by Alliance of Genome Resources, Apr 2025]
Known Variants35 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs150068664 | 11:86,749,111 | C/G | — | uncertain significance |
| rs145333093 | 11:86,749,113 | C/G | — | benign |
| rs1590970511 | 11:86,749,168 | C/T | — | likely benign |
| rs754049323 | 11:86,749,212 | A/G | — | uncertain significance |
| rs981325152 | 11:86,749,217 | C/T | — | uncertain significance |
| rs139866926 | 11:86,778,768 | C/G | — | benign |
| rs145329520 | 11:86,778,801 | A/G | — | benign |
| rs148099893 | 11:86,782,567 | A/G | — | uncertain significance |
| rs75455263 | 11:86,782,663 | A/C | — | benign |
| rs597319 | 11:86,853,997 | A/T | — | — |
| rs477944 | 11:86,860,509 | G/A | intron variant | — |
| rs576679 | 11:86,868,071 | G/C | — | — |
| rs649693 | 11:86,869,577 | T/A | — | — |
| rs664398 | 11:86,870,511 | T/C | intron variant | — |
| rs511755 | 11:86,879,011 | T/A | — | — |
| rs540403 | 11:86,880,458 | G/A | intron variant | — |
| rs505429 | 11:86,886,650 | A/G | intron variant | — |
| rs75937733 | 11:86,905,021 | A/G | intron variant | — |
| rs752037424 | 11:86,947,695 | A/G | — | uncertain significance |
| rs10898646 | 11:86,968,250 | G/A | — | — |
| rs17854687 | 11:87,013,364 | C/T | — | uncertain significance |
| rs2496101068 | 11:87,013,381 | C/T | — | uncertain significance |
| rs35073361 | 11:87,013,393 | T/C | — | benign |
| rs745458620 | 11:87,013,394 | A/G | — | uncertain significance |
| rs146860039 | 11:87,017,001 | G/A | — | likely benign |
| rs267603228 | 11:87,020,649 | C/T | — | uncertain significance |
| rs143844810 | 11:87,020,661 | A/G | — | likely benign |
| rs200088804 | 11:87,029,236 | A/G | — | uncertain significance |
| rs142933575 | 11:87,029,263 | A/G | — | likely benign |
| rs2496142351 | 11:87,029,267 | G/T | — | uncertain significance |
| rs11235097 | 11:87,032,287 | G/C | — | benign |
| rs200127836 | 11:87,032,293 | C/G | — | uncertain significance |
| rs1467125255 | 11:87,032,300 | C/A | — | uncertain significance |
| rs528766082 | 11:87,032,304 | C/G | — | uncertain significance |
| rs141673499 | 11:87,032,321 | G/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.