TOPAZ1
testis and ovary specific TOPAZ 1
Summary
Predicted to be involved in spermatocyte division. Predicted to act upstream of or within apoptotic process; ectopic germ cell programmed cell death; and lncRNA transcription. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants95 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1191417391 | 3:44,283,574 | C/G | — | uncertain significance |
| rs1559520819 | 3:44,283,625 | C/T | — | uncertain significance |
| rs1699485613 | 3:44,283,643 | C/T | — | uncertain significance |
| rs563846176 | 3:44,283,666 | G/A | — | uncertain significance |
| rs2529496296 | 3:44,283,714 | A/C | — | uncertain significance |
| rs528867032 | 3:44,283,729 | G/A | — | uncertain significance |
| rs372299173 | 3:44,283,777 | G/A | — | uncertain significance |
| rs768355986 | 3:44,283,829 | C/T | — | uncertain significance |
| rs2529497332 | 3:44,283,868 | T/G | — | uncertain significance |
| rs375336529 | 3:44,283,873 | T/G | — | uncertain significance |
| rs751189829 | 3:44,283,880 | C/T | — | uncertain significance |
| rs1415543465 | 3:44,284,352 | A/C | — | uncertain significance |
| rs1309001294 | 3:44,284,485 | A/C | — | uncertain significance |
| rs906046922 | 3:44,284,596 | G/A | — | uncertain significance |
| rs765535798 | 3:44,284,635 | A/G | — | uncertain significance |
| rs535849983 | 3:44,284,644 | C/A | — | uncertain significance |
| rs1370232515 | 3:44,284,694 | C/G | — | uncertain significance |
| rs796786257 | 3:44,284,764 | G/A | — | uncertain significance |
| rs549655953 | 3:44,284,791 | C/T | — | likely benign |
| rs923389693 | 3:44,284,855 | A/G | — | uncertain significance |
| rs573616223 | 3:44,284,978 | G/A | — | uncertain significance |
| rs376633336 | 3:44,284,981 | G/A | — | uncertain significance |
| rs267599831 | 3:44,284,997 | G/C | — | uncertain significance |
| rs2529503030 | 3:44,285,113 | C/T | — | uncertain significance |
| rs771933302 | 3:44,285,122 | A/C | — | uncertain significance |
| rs149624505 | 3:44,285,146 | A/G | — | benign |
| rs541758259 | 3:44,285,155 | A/G | — | uncertain significance |
| rs1026584982 | 3:44,285,161 | C/A | — | uncertain significance |
| rs533568766 | 3:44,285,230 | A/G | — | uncertain significance |
| rs183567766 | 3:44,285,248 | A/G | — | uncertain significance |
| rs200454057 | 3:44,285,287 | A/C | — | uncertain significance |
| rs373298781 | 3:44,285,299 | C/T | — | uncertain significance |
| rs1265236681 | 3:44,285,323 | C/T | — | likely benign |
| rs75365049 | 3:44,285,347 | A/G | — | conflicting classifications of pathogenicity |
| rs187914521 | 3:44,285,400 | C/T | — | uncertain significance |
| rs535996097 | 3:44,285,481 | C/T | — | uncertain significance |
| rs750269952 | 3:44,285,514 | T/G | — | uncertain significance |
| rs1445017578 | 3:44,285,530 | C/T | — | uncertain significance |
| rs544974153 | 3:44,285,556 | C/T | — | uncertain significance |
| rs1358682706 | 3:44,285,572 | G/A | — | uncertain significance |
| rs34196405 | 3:44,285,593 | C/T | — | likely benign |
| rs565623606 | 3:44,285,629 | C/T | — | uncertain significance |
| rs2529506129 | 3:44,285,721 | G/A | — | uncertain significance |
| rs1699530515 | 3:44,285,769 | A/G | — | uncertain significance |
| rs1291998613 | 3:44,285,807 | A/T | — | uncertain significance |
| rs528472282 | 3:44,285,823 | A/T | — | uncertain significance |
| rs900856644 | 3:44,285,863 | C/T | — | uncertain significance |
| rs557490730 | 3:44,285,881 | A/G | — | likely benign |
| rs946769034 | 3:44,285,922 | A/G | — | uncertain significance |
| rs1006846324 | 3:44,285,953 | A/G | — | uncertain significance |
| rs1207787522 | 3:44,285,956 | A/G | — | uncertain significance |
| rs993822606 | 3:44,286,008 | T/A | — | likely benign |
| rs2529510004 | 3:44,286,027 | A/G | — | uncertain significance |
| rs767376545 | 3:44,286,045 | C/T | — | uncertain significance |
| rs553103949 | 3:44,286,099 | G/A | — | uncertain significance |
| rs374443327 | 3:44,286,154 | A/G | — | uncertain significance |
| rs114357122 | 3:44,286,207 | A/G | — | benign |
| rs72868354 | 3:44,286,210 | A/G | — | likely benign |
| rs545097523 | 3:44,286,431 | T/A | — | uncertain significance |
| rs2529512272 | 3:44,286,489 | C/G | — | uncertain significance |
| rs866510884 | 3:44,286,579 | G/A | — | uncertain significance |
| rs184177771 | 3:44,286,632 | T/C | — | benign |
| rs976645471 | 3:44,297,694 | T/C | — | uncertain significance |
| rs541531508 | 3:44,297,744 | A/G | — | uncertain significance |
| rs187914231 | 3:44,303,918 | T/C | — | uncertain significance |
| rs917089887 | 3:44,308,548 | C/T | — | uncertain significance |
| rs959036907 | 3:44,310,742 | G/C | — | uncertain significance |
| rs2529574832 | 3:44,310,752 | C/A | — | uncertain significance |
| rs541523820 | 3:44,310,791 | G/A | — | uncertain significance |
| rs1699885862 | 3:44,312,196 | G/A | — | uncertain significance |
| rs2529580276 | 3:44,312,207 | C/A | — | uncertain significance |
| rs141512860 | 3:44,323,076 | A/G | intron variant | — |
| rs938741263 | 3:44,323,463 | T/G | — | uncertain significance |
| rs960569086 | 3:44,328,886 | A/T | — | uncertain significance |
| rs763940561 | 3:44,328,998 | A/T | — | uncertain significance |
| rs1700096020 | 3:44,329,284 | A/G | — | uncertain significance |
| rs191237585 | 3:44,332,303 | A/G | — | uncertain significance |
| rs760375582 | 3:44,332,365 | G/C | — | uncertain significance |
| rs13323323 | 3:44,333,324 | G/T | intron variant | — |
| rs112655871 | 3:44,345,521 | G/A | — | benign |
| rs540278563 | 3:44,346,654 | G/C | — | uncertain significance |
| rs1307150710 | 3:44,346,684 | A/G | — | uncertain significance |
| rs975244763 | 3:44,346,780 | C/A | — | uncertain significance |
| rs11921568 | 3:44,347,833 | A/G | — | benign |
| rs1700336440 | 3:44,347,837 | C/G | — | uncertain significance |
| rs964813150 | 3:44,351,459 | A/G | — | uncertain significance |
| rs1171134774 | 3:44,362,540 | C/T | — | uncertain significance |
| rs554511068 | 3:44,362,664 | A/C | — | benign |
| rs753950103 | 3:44,364,755 | G/A | — | uncertain significance |
| rs1361879162 | 3:44,364,778 | C/T | — | uncertain significance |
| rs1456830822 | 3:44,369,750 | T/C | — | uncertain significance |
| rs780738707 | 3:44,369,790 | G/A | — | uncertain significance |
| rs934216234 | 3:44,373,354 | C/T | — | uncertain significance |
| rs1390626438 | 3:44,373,480 | G/A | — | uncertain significance |
| rs533942526 | 3:44,373,498 | C/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.