TRIM55
tripartite motif containing 55
Summary
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein associates transiently with microtubules, myosin, and titin during muscle sarcomere assembly. It may act as a transient adaptor and plays a regulatory role in the assembly of sarcomeres. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Known Variants45 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs144869282 | 8:67,039,512 | A/G | — | likely benign |
| rs370465107 | 8:67,039,569 | G/A | — | likely benign |
| rs1353011200 | 8:67,039,580 | G/A | — | uncertain significance |
| rs11991549 | 8:67,039,605 | G/A | — | benign |
| rs61760894 | 8:67,040,549 | C/T | — | uncertain significance |
| rs752456346 | 8:67,040,561 | C/T | — | uncertain significance |
| rs2536754657 | 8:67,040,586 | A/T | — | likely benign |
| rs548960401 | 8:67,046,312 | T/C | — | — |
| rs61744335 | 8:67,047,241 | G/T | — | uncertain significance |
| rs150193661 | 8:67,047,274 | C/T | — | uncertain significance |
| rs769305159 | 8:67,047,275 | G/A | — | uncertain significance |
| rs1374275111 | 8:67,047,365 | T/G | — | uncertain significance |
| rs748783640 | 8:67,047,376 | T/C | — | uncertain significance |
| rs74768162 | 8:67,047,384 | A/G | — | likely benign |
| rs144527623 | 8:67,049,375 | C/A | — | likely benign |
| rs57965472 | 8:67,061,980 | G/A | — | likely benign |
| rs141681645 | 8:67,061,983 | C/T | — | uncertain significance |
| rs2536810774 | 8:67,061,991 | G/A | — | uncertain significance |
| rs373480880 | 8:67,062,012 | G/T | — | uncertain significance |
| rs61741078 | 8:67,062,047 | C/T | — | benign |
| rs61738600 | 8:67,062,583 | G/A | — | benign |
| rs149177035 | 8:67,062,689 | G/A | — | uncertain significance |
| rs182072523 | 8:67,062,692 | T/C | — | uncertain significance |
| rs4434604 | 8:67,064,613 | A/G | — | benign |
| rs7843605 | 8:67,064,654 | A/G | — | benign |
| rs544133896 | 8:67,064,674 | G/C | — | uncertain significance |
| rs145620500 | 8:67,064,710 | G/A | — | uncertain significance |
| rs575490972 | 8:67,064,719 | G/A | — | uncertain significance |
| rs1172390685 | 8:67,064,794 | G/T | — | uncertain significance |
| rs574439941 | 8:67,064,825 | C/T | — | uncertain significance |
| rs763066746 | 8:67,064,851 | C/T | — | uncertain significance |
| rs572052118 | 8:67,066,356 | G/A | — | likely benign |
| rs147160216 | 8:67,066,394 | C/T | — | uncertain significance |
| rs1045777754 | 8:67,066,397 | G/A | — | uncertain significance |
| rs369383503 | 8:67,066,405 | A/G | — | uncertain significance |
| rs758591514 | 8:67,066,484 | G/T | — | likely benign |
| rs61745245 | 8:67,066,512 | G/A | — | benign |
| rs761651022 | 8:67,066,534 | G/T | — | uncertain significance |
| rs766527636 | 8:67,066,535 | G/A | — | uncertain significance |
| rs191943450 | 8:67,086,721 | C/T | — | uncertain significance |
| rs552951490 | 8:67,086,731 | A/G | — | uncertain significance |
| rs762038843 | 8:67,086,738 | G/A | — | likely benign |
| rs61753689 | 8:67,086,762 | T/C | — | likely benign |
| rs749269914 | 8:67,086,785 | G/A | — | uncertain significance |
| rs999647192 | 8:67,086,818 | T/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.