TRIM8

tripartite motif containing 8

Summary

This gene encodes a member of the tripartite motif (TRIM) protein family. Based on similarities to other proteins, the encoded protein is suspected to be an E3 ubiquitin-protein ligase. Regulation of this gene may be altered in some cancers. Mutations resulting in a truncated protein product have been observed in early-onset epileptic encephalopathy (EOEE). [provided by RefSeq, Sep 2016]

Known Variants291 total

rsidPosition (GRCh37)AllelesClassClinVar
rs2840868210:104,403,310A/Gcoding sequence variant—
rs414642610:104,404,335A/T—benign
rs213597356110:104,404,375A/G—uncertain significance
rs19950664210:104,404,397G/T—likely benign
rs249288709310:104,404,406A/T—uncertain significance
rs213597357710:104,404,409A/C—uncertain significance
rs249288711910:104,404,410G/C—uncertain significance
rs14085954110:104,404,416C/G—likely benign
rs14311656910:104,404,419C/T—likely benign
rs249288720010:104,404,428C/T—likely benign
rs96461578710:104,404,434C/A—uncertain significance
rs97598988610:104,404,443G/T—likely benign
rs249288724610:104,404,448C/T—uncertain significance
rs76039829310:104,404,464C/T—likely benign
rs138660239310:104,404,468C/G—uncertain significance
rs75654669010:104,404,484G/T—likely benign
rs249288734010:104,404,493G/C—uncertain significance
rs20147159610:104,404,494C/T—likely benign
rs249288739910:104,404,507A/G—uncertain significance
rs123419308010:104,404,510G/A—uncertain significance
rs249288744810:104,404,521C/T—likely benign
rs213597367410:104,404,528T/A—uncertain significance
rs120278608310:104,404,554C/T—likely benign
rs206391935910:104,404,558A/C—uncertain significance
rs96654617810:104,404,563G/C—likely benign
rs77040517810:104,404,564G/T—conflicting classifications of pathogenicity
rs249288754810:104,404,565G/C—likely benign
rs74580822510:104,404,584G/A—likely benign
rs103778444010:104,404,592A/G—uncertain significance
rs249288762310:104,404,605G/A—likely benign
rs76951899710:104,404,612G/A—conflicting classifications of pathogenicity
rs57632595910:104,404,617G/C—likely benign
rs249288767110:104,404,618C/T—likely benign
rs89888942710:104,404,620C/G—likely benign
rs76194389310:104,404,630C/G—likely benign
rs76777679310:104,404,631C/T—likely benign
rs75089624810:104,404,634C/T—likely benign
rs54323106210:104,404,641G/A—likely benign
rs101749720310:104,404,643T/C—likely benign
rs37570523110:104,404,644G/A—likely benign
rs56204855010:104,404,669C/T—uncertain significance
rs249288792810:104,404,686G/T—uncertain significance
rs133464805510:104,404,689G/T—uncertain significance
rs74908867810:104,404,707G/A—benign
rs55518755410:104,404,709C/G—uncertain significance
rs76839394410:104,404,713C/G—likely benign
rs249288802810:104,404,720C/T—uncertain significance
rs249288803610:104,404,724C/T—uncertain significance
rs249288804210:104,404,727A/T—uncertain significance
rs77463342310:104,404,728C/A—uncertain significance
rs76765042410:104,404,731G/A—likely benign
rs206392144810:104,404,743G/A—likely benign
rs249288811510:104,404,753T/G—benign
rs206392158210:104,404,760C/T—likely benign
rs76087543610:104,404,774C/A—uncertain significance
rs88785848710:104,404,783G/A—uncertain significance
rs37405524910:104,404,786G/A—likely benign
rs173266191410:104,404,789G/A—uncertain significance
rs206392193810:104,404,791C/T—likely benign
rs75116525310:104,404,796G/C—uncertain significance
rs147112041810:104,404,800C/T—likely benign
rs75692378210:104,404,809C/T—likely benign
rs78064254510:104,404,822G/T—likely benign
rs249288833810:104,404,824C/T—likely benign
rs249288835810:104,404,833C/G—likely benign
rs249288836710:104,404,842C/T—likely benign
rs118662722110:104,404,845G/A—likely benign
rs249288838710:104,404,852C/T—uncertain significance
rs74925449910:104,404,858G/A—uncertain significance
rs249288841710:104,404,860C/A—likely benign
rs77858967710:104,404,861G/A—uncertain significance
rs123051256610:104,404,893G/C—likely benign
rs249288852010:104,404,901G/T—uncertain significance
rs206392298410:104,404,902A/T—likely benign
rs206392301510:104,404,905C/T—likely benign
rs77712886410:104,404,918G/C—likely benign
rs148371625610:104,404,920G/A—likely benign
rs249288859510:104,404,921G/C—uncertain significance
rs249288861510:104,404,927C/T—uncertain significance
rs249288864110:104,404,939A/T—conflicting classifications of pathogenicity
rs118970673610:104,404,951A/G—likely benign
rs249288875210:104,404,961C/T—likely benign
rs55010031910:104,404,964G/A—likely benign
rs18451226210:104,412,716T/Cintron variant—
rs385069910:104,414,221A/Gintron variant—
rs74723530310:104,414,434C/T—likely benign
rs36850795010:104,414,435G/A—likely benign
rs206400955310:104,414,442G/A—likely benign
rs76004713910:104,414,447G/A—likely benign
rs77611604910:104,414,470C/A—likely benign
rs37114202410:104,414,481C/T—likely benign
rs206400976810:104,414,482G/A—likely benign
rs92574831910:104,414,494C/T—uncertain significance
rs76033866510:104,414,495G/T—uncertain significance
rs206401000010:104,414,517C/T—likely benign
rs77870023610:104,414,523C/T—likely benign
rs120369646610:104,414,818C/T—likely benign
rs127182667810:104,414,830C/T—likely benign
rs76986806210:104,414,832C/T—likely benign
rs37175428010:104,414,833G/A—likely benign

Showing 100 of 291 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.