TRPC4AP
transient receptor potential cation channel subfamily C member 4 associated protein
Summary
Enables phosphatase binding activity and ubiquitin-like ligase-substrate adaptor activity. Involved in protein ubiquitination and ubiquitin-dependent protein catabolic process via the C-end degron rule pathway. Located in cytosol. Part of Cul4A-RING E3 ubiquitin ligase complex. Is active in Cul4-RING E3 ubiquitin ligase complex. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants56 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs201340281 | 20:33,591,005 | C/T | — | uncertain significance |
| rs1359800865 | 20:33,591,074 | T/G | — | uncertain significance |
| rs752075 | 20:33,591,591 | C/A | downstream gene variant | — |
| rs775280311 | 20:33,592,316 | T/C | — | uncertain significance |
| rs755562413 | 20:33,592,335 | T/C | — | uncertain significance |
| rs747346702 | 20:33,592,349 | C/T | — | uncertain significance |
| rs79965102 | 20:33,593,847 | G/A | downstream gene variant | — |
| rs755052500 | 20:33,594,265 | G/C | — | uncertain significance |
| rs139975509 | 20:33,594,301 | C/T | — | likely benign |
| rs2519277930 | 20:33,594,347 | C/G | — | uncertain significance |
| rs1482423053 | 20:33,596,527 | C/G | — | uncertain significance |
| rs184306488 | 20:33,597,720 | A/T | intron variant | — |
| rs376679194 | 20:33,597,994 | C/T | — | uncertain significance |
| rs1885117 | 20:33,600,740 | C/T | intron variant | — |
| rs6087659 | 20:33,606,383 | C/G | — | — |
| rs140177971 | 20:33,606,407 | G/T | — | — |
| rs369517031 | 20:33,608,946 | G/A | regulatory region variant | — |
| rs752598929 | 20:33,609,007 | G/A | — | uncertain significance |
| rs2082881656 | 20:33,609,062 | A/C | — | uncertain significance |
| rs572367487 | 20:33,609,063 | T/A | — | uncertain significance |
| rs182553395 | 20:33,609,075 | A/G | — | uncertain significance |
| rs147516805 | 20:33,609,076 | T/C | — | uncertain significance |
| rs201037229 | 20:33,609,105 | G/A | — | uncertain significance |
| rs2515172914 | 20:33,609,152 | A/C | — | uncertain significance |
| rs192810296 | 20:33,610,106 | G/A | intron variant | — |
| rs201995082 | 20:33,623,039 | G/A | — | uncertain significance |
| rs2083514505 | 20:33,632,311 | G/C | — | uncertain significance |
| rs2515272203 | 20:33,632,337 | A/G | — | uncertain significance |
| rs761178979 | 20:33,632,379 | G/A | — | uncertain significance |
| rs2083517307 | 20:33,632,430 | A/G | — | uncertain significance |
| rs747018659 | 20:33,632,445 | G/C | — | uncertain significance |
| rs1306752143 | 20:33,637,774 | C/G | — | uncertain significance |
| rs140817919 | 20:33,645,338 | T/G | — | uncertain significance |
| rs6087667 | 20:33,651,887 | A/G | intron variant | — |
| rs6120819 | 20:33,653,038 | T/C | intron variant | — |
| rs75377266 | 20:33,656,783 | A/C | — | — |
| rs774403556 | 20:33,657,120 | A/C | — | uncertain significance |
| rs759080326 | 20:33,657,163 | C/G | — | uncertain significance |
| rs6141530 | 20:33,663,147 | T/A | — | — |
| rs755261418 | 20:33,665,911 | G/A | — | uncertain significance |
| rs139800499 | 20:33,665,969 | C/T | — | likely benign |
| rs1353012188 | 20:33,665,973 | G/A | — | uncertain significance |
| rs2180847 | 20:33,667,763 | G/A | — | — |
| rs6119569 | 20:33,672,371 | G/A | intron variant | — |
| rs28536059 | 20:33,674,328 | A/C | — | — |
| rs953055745 | 20:33,680,418 | T/C | — | uncertain significance |
| rs1263648772 | 20:33,680,424 | G/T | — | uncertain significance |
| rs779777585 | 20:33,680,427 | C/A | — | uncertain significance |
| rs748973779 | 20:33,680,428 | G/A | — | uncertain significance |
| rs771531804 | 20:33,680,461 | G/A | — | uncertain significance |
| rs764165080 | 20:33,680,517 | G/A | — | uncertain significance |
| rs1025115040 | 20:33,680,538 | C/G | — | uncertain significance |
| rs753576653 | 20:33,680,545 | G/C | — | uncertain significance |
| rs747738013 | 20:33,680,550 | G/A | — | uncertain significance |
| rs771463865 | 20:33,680,556 | G/C | — | uncertain significance |
| rs768961746 | 20:33,680,580 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.