TTLL11
tubulin tyrosine ligase like 11
Summary
Predicted to enable tubulin binding activity and tubulin-glutamic acid ligase activity. Predicted to be involved in microtubule cytoskeleton organization. Predicted to act upstream of or within microtubule severing and protein polyglutamylation. Predicted to be located in cytosol. Predicted to be active in ciliary basal body. [provided by Alliance of Genome Resources, Apr 2025]
Known Variants49 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs74840871 | 9:124,583,555 | C/G | — | — |
| rs748328447 | 9:124,584,915 | C/T | — | uncertain significance |
| rs557371956 | 9:124,584,916 | G/A | — | likely benign |
| rs771039843 | 9:124,584,976 | G/A | — | uncertain significance |
| rs200414996 | 9:124,584,987 | C/T | — | uncertain significance |
| rs1357298192 | 9:124,584,996 | G/A | — | uncertain significance |
| rs965303542 | 9:124,584,999 | G/T | — | uncertain significance |
| rs564254181 | 9:124,585,003 | C/T | — | uncertain significance |
| rs774750796 | 9:124,585,009 | G/A | — | uncertain significance |
| rs1187615006 | 9:124,585,024 | G/A | — | uncertain significance |
| rs550824818 | 9:124,585,041 | G/T | — | uncertain significance |
| rs916885484 | 9:124,585,046 | G/C | — | uncertain significance |
| rs771166459 | 9:124,585,141 | A/C | — | uncertain significance |
| rs56678373 | 9:124,596,992 | G/A | intron variant | — |
| rs68119843 | 9:124,604,538 | A/T | — | — |
| rs4446794 | 9:124,609,265 | G/A | intron variant | — |
| rs4837905 | 9:124,620,796 | C/A | — | — |
| rs4240470 | 9:124,621,729 | G/C | intron variant | — |
| rs1211281388 | 9:124,622,684 | G/A | — | uncertain significance |
| rs2490386972 | 9:124,622,699 | C/T | — | uncertain significance |
| rs9792407 | 9:124,625,546 | G/C | — | — |
| rs373568909 | 9:124,632,837 | G/A | — | uncertain significance |
| rs61739514 | 9:124,632,869 | C/T | — | uncertain significance |
| rs754101472 | 9:124,633,016 | A/G | — | uncertain significance |
| rs1842661911 | 9:124,737,170 | T/C | — | uncertain significance |
| rs1355721056 | 9:124,737,192 | G/A | — | uncertain significance |
| rs1304428457 | 9:124,737,226 | A/T | — | uncertain significance |
| rs188515711 | 9:124,737,233 | A/C | — | uncertain significance |
| rs746860563 | 9:124,751,574 | A/C | — | uncertain significance |
| rs771316462 | 9:124,751,598 | A/C | — | uncertain significance |
| rs200354661 | 9:124,751,680 | T/A | — | uncertain significance |
| rs775586962 | 9:124,751,734 | G/A | — | uncertain significance |
| rs2490817519 | 9:124,751,755 | G/T | — | uncertain significance |
| rs1218124804 | 9:124,751,756 | C/G | — | uncertain significance |
| rs774508269 | 9:124,751,938 | G/A | — | uncertain significance |
| rs140758256 | 9:124,794,010 | C/T | — | uncertain significance |
| rs2490949966 | 9:124,794,023 | C/G | — | uncertain significance |
| rs138558032 | 9:124,794,046 | G/A | — | uncertain significance |
| rs781560182 | 9:124,855,111 | C/G | — | uncertain significance |
| rs138056066 | 9:124,855,126 | G/A | — | likely benign |
| rs1240911263 | 9:124,855,129 | C/T | — | uncertain significance |
| rs1846304364 | 9:124,855,187 | G/A | — | uncertain significance |
| rs764912568 | 9:124,855,285 | G/C | — | uncertain significance |
| rs1427022629 | 9:124,855,318 | A/G | — | uncertain significance |
| rs903639273 | 9:124,855,404 | G/T | — | likely benign |
| rs956583914 | 9:124,855,418 | C/G | — | uncertain significance |
| rs2490464978 | 9:124,855,531 | G/A | — | uncertain significance |
| rs537954758 | 9:124,855,593 | A/C | — | likely benign |
| rs766810498 | 9:124,855,685 | C/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.