TTLL9
tubulin tyrosine ligase like 9
Summary
Predicted to enable tubulin binding activity and tubulin-glutamic acid ligase activity. Predicted to be involved in flagellated sperm motility and microtubule cytoskeleton organization. Predicted to act upstream of or within protein polyglutamylation. Predicted to be located in cytoplasm; microtubule; and motile cilium. Predicted to be active in ciliary basal body. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants26 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs749750761 | 20:30,475,018 | A/T | — | uncertain significance |
| rs6121264 | 20:30,477,882 | G/C | — | — |
| rs539898837 | 20:30,486,203 | C/T | — | — |
| rs772063026 | 20:30,486,328 | G/A | — | uncertain significance |
| rs369959828 | 20:30,496,411 | T/G | — | uncertain significance |
| rs2515701238 | 20:30,496,453 | A/G | — | uncertain significance |
| rs2063596358 | 20:30,496,459 | A/G | — | uncertain significance |
| rs760256556 | 20:30,496,476 | C/T | — | uncertain significance |
| rs117415805 | 20:30,496,492 | G/T | — | uncertain significance |
| rs373817649 | 20:30,497,547 | G/A | — | uncertain significance |
| rs371713985 | 20:30,497,582 | C/T | — | uncertain significance |
| rs753855660 | 20:30,497,592 | T/G | — | uncertain significance |
| rs776756851 | 20:30,497,663 | G/A | — | uncertain significance |
| rs1183806381 | 20:30,507,671 | C/A | — | uncertain significance |
| rs774245539 | 20:30,507,682 | G/A | — | uncertain significance |
| rs200319476 | 20:30,507,694 | T/C | — | uncertain significance |
| rs753272197 | 20:30,507,710 | T/C | — | uncertain significance |
| rs749750682 | 20:30,510,783 | C/A | — | uncertain significance |
| rs376428616 | 20:30,510,784 | G/A | — | uncertain significance |
| rs750833283 | 20:30,510,850 | A/T | — | uncertain significance |
| rs550977346 | 20:30,512,934 | G/T | — | — |
| rs368625623 | 20:30,525,203 | C/A | — | uncertain significance |
| rs761308678 | 20:30,525,284 | A/G | — | uncertain significance |
| rs538754070 | 20:30,525,285 | C/A | — | uncertain significance |
| rs199514528 | 20:30,525,294 | T/C | — | uncertain significance |
| rs755298072 | 20:30,530,768 | A/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.