VAV2
vav guanine nucleotide exchange factor 2
Summary
VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Known Variants73 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs546006682 | 9:136,629,208 | G/A | — | likely benign |
| rs112576600 | 9:136,633,555 | G/T | — | benign |
| rs765663291 | 9:136,633,566 | G/A | — | uncertain significance |
| rs150483592 | 9:136,633,605 | C/T | — | uncertain significance |
| rs138753594 | 9:136,633,640 | C/T | — | uncertain significance |
| rs183141718 | 9:136,634,554 | C/T | — | uncertain significance |
| rs756680997 | 9:136,635,529 | G/A | — | uncertain significance |
| rs758798561 | 9:136,637,163 | T/C | — | uncertain significance |
| rs762272210 | 9:136,640,085 | C/T | — | uncertain significance |
| rs750643570 | 9:136,640,088 | C/A | — | uncertain significance |
| rs7875953 | 9:136,640,122 | G/A | — | benign |
| rs1348655623 | 9:136,641,162 | G/A | — | uncertain significance |
| rs147799977 | 9:136,641,177 | C/T | — | uncertain significance |
| rs772588253 | 9:136,641,178 | G/A | — | uncertain significance |
| rs780462649 | 9:136,642,581 | C/T | — | uncertain significance |
| rs139458505 | 9:136,642,590 | C/G | — | benign |
| rs145229236 | 9:136,643,935 | C/G | — | benign |
| rs776157987 | 9:136,645,058 | C/T | — | uncertain significance |
| rs111868428 | 9:136,645,059 | G/A | — | benign |
| rs184909763 | 9:136,649,489 | C/T | — | uncertain significance |
| rs1254038497 | 9:136,649,514 | T/C | — | uncertain significance |
| rs150054284 | 9:136,649,515 | T/C | — | uncertain significance |
| rs144398774 | 9:136,649,529 | T/C | — | uncertain significance |
| rs748269402 | 9:136,649,548 | G/C | — | uncertain significance |
| rs768234718 | 9:136,650,918 | C/T | — | uncertain significance |
| rs150924742 | 9:136,653,484 | C/G | — | uncertain significance |
| rs2538792539 | 9:136,653,539 | C/G | — | uncertain significance |
| rs56296048 | 9:136,653,551 | G/A | — | benign |
| rs761914102 | 9:136,653,577 | C/T | — | uncertain significance |
| rs138063876 | 9:136,656,916 | T/C | — | uncertain significance |
| rs752765700 | 9:136,656,960 | C/T | — | uncertain significance |
| rs573366869 | 9:136,658,511 | A/C | — | — |
| rs61761612 | 9:136,660,845 | T/A | — | uncertain significance |
| rs143721504 | 9:136,661,595 | C/G | — | uncertain significance |
| rs2538819805 | 9:136,661,602 | G/T | — | uncertain significance |
| rs767286250 | 9:136,661,622 | C/G | — | uncertain significance |
| rs568453790 | 9:136,662,834 | C/T | — | uncertain significance |
| rs1564365196 | 9:136,671,246 | C/T | — | uncertain significance |
| rs767232783 | 9:136,671,285 | G/A | — | uncertain significance |
| rs1588201650 | 9:136,671,295 | G/T | — | likely benign |
| rs114046743 | 9:136,672,374 | C/G | — | likely benign |
| rs377331945 | 9:136,672,403 | C/T | — | uncertain significance |
| rs2538848693 | 9:136,672,405 | A/G | — | uncertain significance |
| rs544726882 | 9:136,673,487 | C/G | — | — |
| rs769651196 | 9:136,674,245 | C/T | — | uncertain significance |
| rs2538854937 | 9:136,674,254 | C/A | — | uncertain significance |
| rs7021663 | 9:136,676,014 | T/C | regulatory region variant | — |
| rs200161328 | 9:136,677,227 | A/G | — | likely benign |
| rs766541095 | 9:136,677,284 | C/T | — | likely benign |
| rs148600123 | 9:136,677,338 | G/A | — | likely benign |
| rs756777 | 9:136,679,080 | A/G | intron variant | — |
| rs561460341 | 9:136,698,045 | C/T | — | — |
| rs774257474 | 9:136,699,415 | C/T | — | uncertain significance |
| rs2538931002 | 9:136,699,424 | T/C | — | uncertain significance |
| rs1325408097 | 9:136,699,455 | G/A | — | uncertain significance |
| rs2156323 | 9:136,720,821 | G/A | regulatory region variant | — |
| rs10993828 | 9:136,721,668 | A/C | regulatory region variant | — |
| rs12344583 | 9:136,723,520 | A/G | intron variant | — |
| rs759182638 | 9:136,726,502 | C/T | — | uncertain significance |
| rs973702754 | 9:136,726,511 | T/C | — | uncertain significance |
| rs145591299 | 9:136,726,513 | C/T | — | likely benign |
| rs564658959 | 9:136,726,514 | G/A | — | uncertain significance |
| rs12342989 | 9:136,726,546 | G/A | — | benign |
| rs118109295 | 9:136,796,848 | G/A | intron variant | — |
| rs766660632 | 9:136,804,238 | C/T | — | uncertain significance |
| rs2539239135 | 9:136,804,259 | G/A | — | uncertain significance |
| rs1174175420 | 9:136,804,289 | A/T | — | uncertain significance |
| rs1633764 | 9:136,817,448 | G/C | intron variant | — |
| rs3780792 | 9:136,835,343 | A/G | intron variant | — |
| rs112628278 | 9:136,846,796 | T/C | intron variant | — |
| rs767762962 | 9:136,857,223 | T/A | — | uncertain significance |
| rs2539424338 | 9:136,857,266 | C/G | — | uncertain significance |
| rs765191899 | 9:136,857,342 | T/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.