WDR41
WD repeat domain 41
Summary
Enables GTPase activator activity. Contributes to guanyl-nucleotide exchange factor activity. Involved in regulation of autophagy. Located in cytoplasm. Part of guanyl-nucleotide exchange factor complex. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants30 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs767400816 | 5:76,729,033 | C/T | — | uncertain significance |
| rs146353207 | 5:76,729,070 | C/T | — | uncertain significance |
| rs1449531771 | 5:76,732,129 | A/G | — | uncertain significance |
| rs181961877 | 5:76,732,130 | G/C | — | uncertain significance |
| rs997917836 | 5:76,732,135 | C/G | — | uncertain significance |
| rs746933124 | 5:76,732,146 | A/C | — | uncertain significance |
| rs2532684299 | 5:76,732,147 | T/C | — | uncertain significance |
| rs2532690482 | 5:76,733,175 | T/G | — | uncertain significance |
| rs2532690765 | 5:76,733,197 | C/G | — | uncertain significance |
| rs148644268 | 5:76,734,071 | G/A | — | uncertain significance |
| rs139122408 | 5:76,734,104 | T/C | — | uncertain significance |
| rs1799026115 | 5:76,734,138 | T/C | — | uncertain significance |
| rs1484431705 | 5:76,734,185 | T/C | — | uncertain significance |
| rs146405822 | 5:76,736,673 | C/T | — | uncertain significance |
| rs1464201035 | 5:76,736,760 | T/C | — | uncertain significance |
| rs547495928 | 5:76,736,796 | C/T | — | likely benign |
| rs560546550 | 5:76,742,615 | G/C | — | — |
| rs163016 | 5:76,743,481 | A/C | — | — |
| rs755888280 | 5:76,749,714 | C/T | — | uncertain significance |
| rs768315489 | 5:76,749,725 | A/G | — | uncertain significance |
| rs572699452 | 5:76,749,732 | G/C | — | uncertain significance |
| rs764129147 | 5:76,754,919 | G/C | — | uncertain significance |
| rs887391346 | 5:76,760,629 | G/T | — | uncertain significance |
| rs163030 | 5:76,781,471 | A/G | — | — |
| rs200398499 | 5:76,785,348 | G/T | — | uncertain significance |
| rs2530693599 | 5:76,785,373 | C/T | — | uncertain significance |
| rs374435941 | 5:76,787,996 | T/G | — | uncertain significance |
| rs552575847 | 5:76,842,088 | A/G | coding sequence variant | — |
| rs13361688 | 5:76,866,655 | G/A | intron variant | — |
| rs137887044 | 5:76,912,498 | C/T | regulatory region variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.