WDR75
WD repeat domain 75
Summary
Enables RNA binding activity. Involved in positive regulation of rRNA processing; positive regulation of transcription by RNA polymerase I; and ribosomal small subunit biogenesis. Located in nucleolus. Part of small-subunit processome. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants31 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs770817824 | 2:190,306,241 | G/T | — | uncertain significance |
| rs761288211 | 2:190,313,131 | T/C | — | uncertain significance |
| rs1481414447 | 2:190,313,189 | A/C | — | uncertain significance |
| rs750041271 | 2:190,316,602 | A/G | — | uncertain significance |
| rs781176884 | 2:190,316,613 | A/G | — | uncertain significance |
| rs1686712012 | 2:190,320,118 | T/C | — | uncertain significance |
| rs562776153 | 2:190,322,058 | C/T | — | uncertain significance |
| rs978949559 | 2:190,323,529 | C/T | — | uncertain significance |
| rs368856476 | 2:190,323,577 | T/C | — | uncertain significance |
| rs2468673532 | 2:190,324,087 | T/C | — | uncertain significance |
| rs779064956 | 2:190,324,118 | A/G | — | uncertain significance |
| rs1321880005 | 2:190,324,127 | T/G | — | uncertain significance |
| rs147809896 | 2:190,327,230 | G/A | — | uncertain significance |
| rs528766591 | 2:190,327,234 | G/T | — | uncertain significance |
| rs777266750 | 2:190,327,255 | G/T | — | uncertain significance |
| rs148423434 | 2:190,327,258 | G/A | — | uncertain significance |
| rs2468677004 | 2:190,327,340 | T/A | — | uncertain significance |
| rs756258509 | 2:190,329,913 | C/G | — | uncertain significance |
| rs141018007 | 2:190,329,929 | C/T | — | uncertain significance |
| rs1443821678 | 2:190,331,231 | A/G | — | uncertain significance |
| rs370434777 | 2:190,331,283 | A/G | — | uncertain significance |
| rs1016609102 | 2:190,332,232 | T/A | — | uncertain significance |
| rs773207890 | 2:190,332,260 | G/T | — | uncertain significance |
| rs567402066 | 2:190,332,315 | A/G | — | uncertain significance |
| rs116384530 | 2:190,332,547 | A/G | intron variant | — |
| rs773690910 | 2:190,334,141 | T/C | — | uncertain significance |
| rs2468689277 | 2:190,335,603 | A/C | — | uncertain significance |
| rs757758986 | 2:190,339,011 | G/A | — | uncertain significance |
| rs151070438 | 2:190,339,047 | G/T | — | uncertain significance |
| rs756382713 | 2:190,339,979 | A/G | — | uncertain significance |
| rs370533793 | 2:190,340,063 | A/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.