WNT16
Wnt family member 16
Summary
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It contains two transcript variants diverging at the 5' termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. They are differentially expressed in normal tissues, one of which (variant 2) is expressed at significant levels only in the pancreas, whereas another one (variant 1) is expressed more ubiquitously with highest levels in adult kidney, placenta, brain, heart, and spleen. [provided by RefSeq, Jul 2008]
Known Variants26 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs200837511 | 7:120,969,671 | A/G | — | uncertain significance |
| rs1191111101 | 7:120,969,715 | C/T | — | uncertain significance |
| rs1364147111 | 7:120,969,746 | C/A | — | uncertain significance |
| rs2908004 | 7:120,969,769 | G/A | missense variant | — |
| rs116194910 | 7:120,969,786 | C/G | — | uncertain significance |
| rs1025795788 | 7:120,969,791 | G/A | — | uncertain significance |
| rs773585692 | 7:120,969,808 | A/G | — | likely benign |
| rs17143291 | 7:120,969,825 | C/A | — | benign |
| rs1174604219 | 7:120,971,837 | C/T | — | uncertain significance |
| rs1245221970 | 7:120,971,953 | A/T | — | uncertain significance |
| rs770544427 | 7:120,971,983 | G/A | — | uncertain significance |
| rs2536189 | 7:120,973,621 | C/G | intron variant | — |
| rs3801387 | 7:120,974,765 | A/C | — | — |
| rs2707469 | 7:120,976,886 | A/G | regulatory region variant | — |
| rs55963900 | 7:120,977,734 | G/A | regulatory region variant | — |
| rs183788812 | 7:120,978,983 | G/A | — | uncertain significance |
| rs372183865 | 7:120,978,989 | T/A | — | uncertain significance |
| rs748941129 | 7:120,979,037 | G/A | — | uncertain significance |
| rs771869104 | 7:120,979,058 | T/C | — | uncertain significance |
| rs116444834 | 7:120,979,079 | T/C | — | benign |
| rs2707466 | 7:120,979,089 | C/T | missense variant | — |
| rs763281050 | 7:120,979,103 | C/T | — | uncertain significance |
| rs143771072 | 7:120,979,164 | A/G | — | uncertain significance |
| rs773392753 | 7:120,979,179 | A/C | — | uncertain significance |
| rs1361670178 | 7:120,979,250 | G/A | — | uncertain significance |
| rs772403126 | 7:120,979,310 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.