YEATS4
YEATS domain containing 4
Summary
The protein encoded by this gene is found in the nucleoli. It has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. This gene has been shown to be amplified in tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Known Variants13 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs645026 | 12:69,757,931 | G/C | — | — |
| rs315135 | 12:69,762,987 | A/G | intron variant | — |
| rs4622313 | 12:69,768,985 | C/G | — | — |
| rs73151676 | 12:69,770,312 | C/T | intron variant | — |
| rs315122 | 12:69,771,073 | G/A | — | — |
| rs7954034 | 12:69,796,800 | G/A | downstream gene variant | — |
| rs12367674 | 12:69,812,494 | C/T | — | — |
| rs7297610 | 12:69,824,024 | C/T | intergenic variant | — |
| rs10748128 | 12:69,827,658 | G/C | — | — |
| rs10878984 | 12:69,828,534 | C/T | intergenic variant | — |
| rs11177669 | 12:69,828,681 | G/C | — | — |
| rs11177674 | 12:69,834,545 | C/T | intergenic variant | — |
| rs7296920 | 12:69,836,521 | G/A | intergenic variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.