ZFYVE28
zinc finger FYVE-type containing 28
Summary
Enables phosphatidylinositol-3-phosphate binding activity. Involved in negative regulation of epidermal growth factor-activated receptor activity. Located in cytosol and early endosome membrane. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants77 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs575982537 | 4:2,272,522 | G/A | — | uncertain significance |
| rs1367189870 | 4:2,272,561 | G/A | — | uncertain significance |
| rs761139102 | 4:2,272,578 | G/C | — | uncertain significance |
| rs199601247 | 4:2,273,099 | G/A | — | likely benign |
| rs201539304 | 4:2,273,138 | G/C | — | uncertain significance |
| rs150242683 | 4:2,274,995 | G/A | — | uncertain significance |
| rs748163383 | 4:2,275,801 | C/T | — | uncertain significance |
| rs367798999 | 4:2,275,831 | C/T | — | uncertain significance |
| rs1159653957 | 4:2,275,846 | G/A | — | uncertain significance |
| rs2108798538 | 4:2,275,860 | G/A | — | uncertain significance |
| rs778276843 | 4:2,275,896 | G/A | — | likely benign |
| rs4602560 | 4:2,292,921 | A/G | regulatory region variant | — |
| rs556625985 | 4:2,306,044 | C/T | — | uncertain significance |
| rs112076615 | 4:2,306,045 | G/A | — | benign |
| rs764441401 | 4:2,306,047 | G/C | — | uncertain significance |
| rs1467650622 | 4:2,306,049 | G/A | — | uncertain significance |
| rs375668662 | 4:2,306,056 | G/A | — | uncertain significance |
| rs768638735 | 4:2,306,057 | G/T | — | uncertain significance |
| rs772852130 | 4:2,306,130 | G/A | — | uncertain significance |
| rs2108822802 | 4:2,306,164 | G/C | — | uncertain significance |
| rs142096366 | 4:2,306,229 | G/A | — | uncertain significance |
| rs752787096 | 4:2,306,250 | G/A | — | uncertain significance |
| rs149217247 | 4:2,306,275 | C/A | — | uncertain significance |
| rs377668860 | 4:2,306,277 | G/A | — | likely benign |
| rs139020803 | 4:2,306,286 | G/A | — | uncertain significance |
| rs1212032990 | 4:2,306,295 | A/G | — | uncertain significance |
| rs771357502 | 4:2,306,326 | G/T | — | uncertain significance |
| rs147422794 | 4:2,306,440 | C/T | — | uncertain significance |
| rs371841906 | 4:2,306,446 | C/T | — | uncertain significance |
| rs199748984 | 4:2,306,454 | G/A | — | uncertain significance |
| rs753399338 | 4:2,306,457 | G/A | — | uncertain significance |
| rs774644261 | 4:2,306,460 | G/A | — | uncertain significance |
| rs151169783 | 4:2,306,499 | G/A | — | uncertain significance |
| rs200468587 | 4:2,306,542 | C/T | — | uncertain significance |
| rs772727363 | 4:2,306,557 | T/C | — | uncertain significance |
| rs1560173052 | 4:2,306,562 | T/C | — | uncertain significance |
| rs753184462 | 4:2,306,568 | G/A | — | uncertain significance |
| rs2474108784 | 4:2,306,608 | G/A | — | likely benign |
| rs377484299 | 4:2,306,616 | G/A | — | uncertain significance |
| rs765688641 | 4:2,306,637 | C/T | — | likely benign |
| rs780016186 | 4:2,306,643 | C/G | — | uncertain significance |
| rs114467899 | 4:2,306,696 | G/T | — | benign |
| rs377628449 | 4:2,306,712 | G/A | — | uncertain significance |
| rs974943231 | 4:2,306,725 | T/C | — | uncertain significance |
| rs776479164 | 4:2,306,731 | C/A | — | uncertain significance |
| rs139543749 | 4:2,306,736 | G/A | — | uncertain significance |
| rs758071176 | 4:2,306,771 | G/T | — | uncertain significance |
| rs906850002 | 4:2,306,776 | C/G | — | uncertain significance |
| rs761629764 | 4:2,306,818 | C/T | — | uncertain significance |
| rs779341433 | 4:2,306,851 | C/T | — | uncertain significance |
| rs200292647 | 4:2,306,872 | G/A | — | uncertain significance |
| rs202196380 | 4:2,306,882 | G/C | — | likely benign |
| rs142322588 | 4:2,306,904 | G/A | — | uncertain significance |
| rs770050661 | 4:2,306,949 | G/C | — | uncertain significance |
| rs141682211 | 4:2,307,087 | G/A | — | uncertain significance |
| rs2474110290 | 4:2,307,116 | C/G | — | uncertain significance |
| rs61742112 | 4:2,307,121 | A/G | — | benign |
| rs143836367 | 4:2,307,125 | G/C | — | benign |
| rs546914554 | 4:2,307,169 | C/T | — | uncertain significance |
| rs141242318 | 4:2,307,178 | G/C | — | uncertain significance |
| rs559207225 | 4:2,307,217 | G/A | — | uncertain significance |
| rs1430391131 | 4:2,307,235 | C/G | — | uncertain significance |
| rs200537981 | 4:2,321,906 | C/T | — | uncertain significance |
| rs1227955666 | 4:2,321,928 | G/A | — | uncertain significance |
| rs375076072 | 4:2,321,957 | C/T | — | uncertain significance |
| rs79194530 | 4:2,324,192 | G/A | upstream gene variant | — |
| rs142324069 | 4:2,341,280 | C/T | — | uncertain significance |
| rs2474178123 | 4:2,341,300 | C/G | — | uncertain significance |
| rs750637197 | 4:2,355,650 | C/T | — | likely benign |
| rs374684774 | 4:2,355,713 | G/A | — | uncertain significance |
| rs765834074 | 4:2,355,796 | G/A | — | uncertain significance |
| rs959770 | 4:2,395,297 | A/C | — | — |
| rs116608013 | 4:2,397,776 | A/G | — | — |
| rs142763632 | 4:2,406,483 | G/C | intron variant | — |
| rs75385950 | 4:2,406,792 | T/C | intron variant | — |
| rs745519973 | 4:2,420,013 | T/C | — | uncertain significance |
| rs1438306748 | 4:2,420,043 | T/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.