ZNF732
zinc finger protein 732
Summary
This gene encodes a kruppel-associated box-containing zinc finger protein (KRAB-ZFP). The encoded protein contains an N-terminal kruppel-associated box (KRAB) domain and sixteen C-terminal C2H2-type zinc finger domains. The KRAB-ZFPs represent the largest family of mammalian transcriptional repressors, which function through the recruitment of the nuclear co-factor KRAB-Associated Protein 1 (KAP1), to engage histone modifiers and induce heterochromatin formation. [provided by RefSeq, Jul 2017]
Known Variants48 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2474122704 | 4:264,892 | A/G | — | uncertain significance |
| rs1719343307 | 4:264,896 | T/G | — | uncertain significance |
| rs1304079032 | 4:264,905 | T/C | — | uncertain significance |
| rs2474122747 | 4:264,908 | A/C | — | uncertain significance |
| rs1364929102 | 4:264,915 | A/C | — | uncertain significance |
| rs2474122792 | 4:264,922 | T/G | — | uncertain significance |
| rs570112191 | 4:264,924 | A/C | — | uncertain significance |
| rs782807148 | 4:265,025 | G/A | — | uncertain significance |
| rs782605604 | 4:265,072 | G/T | — | uncertain significance |
| rs782233438 | 4:265,073 | T/C | — | uncertain significance |
| rs1424412941 | 4:265,075 | T/C | — | uncertain significance |
| rs781801615 | 4:265,103 | T/C | — | uncertain significance |
| rs782534382 | 4:265,163 | T/C | — | uncertain significance |
| rs2474123270 | 4:265,171 | T/C | — | uncertain significance |
| rs201614981 | 4:265,195 | A/C | — | likely benign |
| rs782774524 | 4:265,238 | C/T | — | uncertain significance |
| rs782574291 | 4:265,249 | T/A | — | uncertain significance |
| rs782009847 | 4:265,303 | C/T | — | uncertain significance |
| rs369875361 | 4:265,333 | A/G | — | uncertain significance |
| rs61792065 | 4:265,355 | T/C | — | uncertain significance |
| rs1321401478 | 4:265,466 | C/T | — | uncertain significance |
| rs782070059 | 4:265,507 | T/C | — | uncertain significance |
| rs781949677 | 4:265,529 | G/T | — | uncertain significance |
| rs2474124845 | 4:265,564 | G/A | — | uncertain significance |
| rs542750425 | 4:265,664 | G/A | — | uncertain significance |
| rs543902053 | 4:265,709 | T/C | — | uncertain significance |
| rs375952545 | 4:265,742 | C/T | — | likely benign |
| rs1553837690 | 4:265,748 | G/T | — | uncertain significance |
| rs782584256 | 4:265,922 | T/C | — | uncertain significance |
| rs375346370 | 4:265,924 | T/A | — | uncertain significance |
| rs1034554757 | 4:265,925 | G/C | — | uncertain significance |
| rs1719394057 | 4:265,934 | A/G | — | uncertain significance |
| rs369852834 | 4:266,093 | G/A | — | uncertain significance |
| rs374966989 | 4:266,112 | C/G | — | uncertain significance |
| rs200473584 | 4:266,170 | C/T | — | likely benign |
| rs782319841 | 4:266,177 | T/C | — | uncertain significance |
| rs1553837940 | 4:266,209 | T/C | — | uncertain significance |
| rs782626157 | 4:266,350 | A/G | — | uncertain significance |
| rs553409844 | 4:266,417 | C/G | — | uncertain significance |
| rs11723261 | 4:282,499 | A/G | intron variant | — |
| rs112253195 | 4:289,244 | G/A | — | uncertain significance |
| rs190712898 | 4:289,254 | T/C | — | uncertain significance |
| rs781938228 | 4:289,314 | T/C | — | uncertain significance |
| rs1719929591 | 4:289,321 | A/G | — | likely benign |
| rs782238744 | 4:289,827 | T/C | — | likely benign |
| rs2474150567 | 4:289,869 | T/C | — | uncertain significance |
| rs150582722 | 4:291,488 | A/T | intron variant | — |
| rs138735623 | 4:293,297 | C/T | intron variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.