ZRANB1
zinc finger RANBP2-type containing 1
Summary
Enables K63-linked polyubiquitin modification-dependent protein binding activity and cysteine-type deubiquitinase activity. Involved in several processes, including positive regulation of Wnt signaling pathway; protein deubiquitination; and regulation of cell morphogenesis. Located in cytosol and nucleoplasm. Is active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants28 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs191058502 | 10:126,628,420 | T/C | upstream gene variant | — |
| rs72828952 | 10:126,629,608 | A/G | upstream gene variant | — |
| rs145369942 | 10:126,631,307 | T/A | — | uncertain significance |
| rs1951548091 | 10:126,631,334 | A/G | — | uncertain significance |
| rs538702549 | 10:126,631,447 | C/T | — | uncertain significance |
| rs1263387555 | 10:126,631,551 | G/C | — | uncertain significance |
| rs767922815 | 10:126,631,595 | A/G | — | uncertain significance |
| rs750198687 | 10:126,631,604 | A/G | — | uncertain significance |
| rs772654803 | 10:126,631,642 | A/G | — | uncertain significance |
| rs778584834 | 10:126,631,721 | C/T | — | uncertain significance |
| rs372066172 | 10:126,631,726 | C/T | — | uncertain significance |
| rs971164575 | 10:126,631,727 | G/A | — | uncertain significance |
| rs747474149 | 10:126,631,864 | A/C | — | uncertain significance |
| rs17152408 | 10:126,649,007 | G/A | intron variant | — |
| rs17152411 | 10:126,649,516 | A/C | — | — |
| rs2114834 | 10:126,650,186 | A/T | — | — |
| rs369720358 | 10:126,655,237 | G/A | — | uncertain significance |
| rs371243108 | 10:126,655,336 | A/G | — | uncertain significance |
| rs2538905374 | 10:126,655,337 | T/C | — | uncertain significance |
| rs778022551 | 10:126,660,649 | A/G | — | uncertain significance |
| rs1266621602 | 10:126,660,653 | T/G | — | uncertain significance |
| rs746609058 | 10:126,662,216 | A/G | — | uncertain significance |
| rs2538914862 | 10:126,662,235 | C/G | — | uncertain significance |
| rs75293113 | 10:126,671,767 | G/T | — | benign |
| rs763456016 | 10:126,672,145 | A/G | — | uncertain significance |
| rs779937717 | 10:126,673,439 | C/T | — | uncertain significance |
| rs189374953 | 10:126,673,442 | C/T | — | uncertain significance |
| rs761222098 | 10:126,673,505 | C/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.