rs10035291
This is a intron variant variant in the SSBP2 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
bipolar disorder
Li HJ et al. “Novel Risk Loci Associated With Genetic Risk for Bipolar Disorder Among Han Chinese Individuals: A Genome-Wide Association Study and Meta-analysis.” Jama Psychiatry 78(3):320-330 (2021)
Allele T
OR 1.07
p 3.0e-8
N 58,182
Meta-analysisLarge GWAS
multi-ancestry
Stahl EA et al. “Genome-wide association study identifies 30 loci associated with bipolar disorder.” Nature Genetics 51(5):793-803 (2019)
Allele T
OR 1.07
p 3.0e-8
N 51,710
Large GWAS
European
About SSBP2
This gene encodes a subunit of a protein complex that interacts with single-stranded DNA and is involved in the DNA damage response and maintenance of genome stability. The encoded protein may also play a role in telomere repair. A variant of this gene may be associated with survival in human glioblastoma patients. [provided by RefSeq, Sep 2016]
View all SSBP2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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