rs10035961
This is a regulatory region variant variant.
▶Research that mentions this SNP (1)
▶A narrow and highly significant linkage signal for severe bipolar disorder in the chromosome 5q33 region in Latin American pedigreesAssociationN=592Jasinska AJ et al.(2009)· American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
This study reports a narrow and highly significant linkage signal for bipolar disorder type I (BP-I) on chromosome 5q33 in Costa Rican and Colombian pedigrees. Fine-mapping with 1,134 SNPs yielded a combined LOD score of 4.9 at rs10035961 (156.9 Mb), with two additional SNPs (rs7721142 and rs1422795) also showing LOD>4 in a 94 kb region. Population-based association analysis identified signals at rs12523547 (P=0.00004) and rs267015 (P=0.00016), though these did not clearly overlap with the linkage peak, suggesting possible allelic or locus heterogeneity.
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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