rs10048146

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GWAS Catalog Trait Associations (9)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

body height

Yengo L et al. “A saturated map of common genetic variants associated with human height.” Nature 610(7933):704-712 (2022)
Allele G
OR 0.01
p 2.0e-74
N 5,314,291
Large GWAS
European, Hispanic or Latin American, East Asian, African unspecified, South Asian

brain attribute

van der Meer D et al. “The genetic architecture of human cortical folding.” Science Advances 7(51):eabj9446 (2021)
Allele G
OR 14.07
p 6.0e-45
N 33,748
Large GWAS
European

cerebral cortex area attribute

van der Meer D et al. “The genetic architecture of human cortical folding.” Science Advances 7(51):eabj9446 (2021)
Allele G
OR 9.33
p 1.0e-20
N 33,748
Large GWAS
European
Shadrin AA et al. “Vertex-wise multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology.” Neuroimage 244:118603 (2021)
Allele G
OR —
p 1.0e-17
N 35,657
Large GWAS
European

femoral neck bone mineral density

Estrada K et al. “Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.” Nature Genetics 44(5):491-501 (2012)
Allele A
OR —
β 0.050
p 1.0e-14
N 32,961
Meta-analysisLarge GWAS
multi-ancestry

dental caries, dentures

Shungin D et al. “Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data.” Nature Communications 10(1):2773 (2019)
Allele A
OR 0.03
p 5.0e-14
N 487,823
Large GWAS
multi-ancestry

dentures

Shungin D et al. “Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data.” Nature Communications 10(1):2773 (2019)
Allele A
OR 0.05
p 4.0e-13
N 461,031
Large GWAS
European

dental caries

Nogawa S et al. “Genome-wide association meta-analysis identifies two novel loci associated with dental caries.” Bmc Oral Health 24(1):1003 (2024)
Allele G
OR 6.89
p 6.0e-12
N 533,348
Meta-analysisLarge GWAS
multi-ancestry

brain volume

Smith SM et al. “An expanded set of genome-wide association studies of brain imaging phenotypes in UK Biobank.” Nature Neuroscience 24(5):737-745 (2021)
Allele G
OR 0.07
p 1.0e-8
N 22,133
Major Consortium StudyLarge GWAS
European

bone tissue density

Rivadeneira F et al. “Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.” Nature Genetics 41(11):1199-206 (2009)
Allele G
OR 0.09
p 2.0e-8
N 19,195
Meta-analysisLarge GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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