rs1005002
This is a intron variant variant in the NDP gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
primary aldosteronism
Le Floch E et al. “Identification of risk loci for primary aldosteronism in genome-wide association studies.” Nature Communications 13(1):5198 (2022)
Allele A
OR 1.41
p 1.0e-9
N 978
Small GWAS
European
About NDP
This gene encodes a secreted protein with a cystein-knot motif that activates the Wnt/beta-catenin pathway. The protein forms disulfide-linked oligomers in the extracellular matrix. Mutations in this gene result in Norrie disease and X-linked exudative vitreoretinopathy. [provided by RefSeq, Feb 2009]
View all NDP variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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