rs1005390

This is a intron variant variant in the LOC105375567 gene.

GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

4-acetamidobutanoate-to-X-03056--N-[3-(2-Oxopyrrolidin-1-yl)propyl]acetamide ratio

Shin SY et al. An atlas of genetic influences on human blood metabolites. Nature Genetics 46(6):543-550 (2014)
Allele T
OR
β 0.035
p 3.0e-16
N 4,910
Large GWAS
European

X-03056--N-[3- 2-Oxopyrrolidin-1-yl propyl]acetamide measurement

Shin SY et al. An atlas of genetic influences on human blood metabolites. Nature Genetics 46(6):543-550 (2014)
Allele T
OR 0.03
p 3.0e-14
N 7,812
Large GWAS
European

1-methylhistamine measurement

Feofanova EV et al. Whole-Genome Sequencing Analysis of Human Metabolome in Multi-Ethnic Populations. Nature Communications 14(1):3111 (2023)
Allele G
OR 0.15
p 8.0e-12
N 6,915
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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