rs1006899
This is a intergenic variant variant.
▶Research that mentions this SNP (1)
▶Replication study of candidate genes/loci associated with osteoporosis based on genome-wide screeningAssociationN=1,000Zhang YP et al.(2010)· Osteoporosis International
Replication study of candidate genes/loci associated with osteoporosis based on genome-wide screening
AssociationN=1,000Zhang YP et al.(2010)· Osteoporosis International
A replication study of 139 SNPs from three prior genome-wide association studies of bone mineral density in an independent sample of 1,000 unrelated US whites confirmed 38 SNPs (27% replication rate). Two SNPs achieved the most significant replication: rs3762397 in NR5A2 and rs3736228 in LRP5. Ten SNPs achieved combined p-values less than 3.6×10⁻⁴ across datasets, including rs3736228 (LRP5) with combined p=5.3×10⁻¹² for spinal BMD.
Traits studied:Bone mineral densityFemoral neck bone mineral density (FNBMD)Hip bone mineral density (HIPBMD)OsteoporosisSpinal bone mineral density (SPNBMD)
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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