rs10076436
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
electrocardiography
Tereshchenko LG et al. “Genome-Wide Associations of Global Electrical Heterogeneity ECG Phenotype: The ARIC (Atherosclerosis Risk in Communities) Study and CHS (Cardiovascular Health Study).” Journal of the American Heart Association 7(8) (2018)
Allele C
OR 0.12
p 2.0e-20
N 13,826
CohortLarge GWAS
multi-ancestry
QRS duration
van Setten J et al. “Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits.” European Journal of Human Genetics : Ejhg 27(6):952-962 (2019)
Allele G
OR 0.81
p 1.0e-18
N 25,509
Meta-analysisLarge GWAS
multi-ancestry
left ventricular structural measurement
Meyer HV et al. “Genetic and functional insights into the fractal structure of the heart.” Nature 584(7822):589-594 (2020)
Allele G
OR 0.08
p 3.0e-12
N 18,096
Large GWAS
European
QRS-T angle
Young WJ et al. “Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease.” Nature Communications 14(1):1411 (2023)
Allele C
OR 0.08
p 6.0e-55
N 96,562
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…