rs1008078

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

self reported educational attainment

Lee JJ et al. “Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.” Nature Genetics 50(8):1112-1121 (2018)

Allele T

OR 0.02

p 6.0e-41

N 1,311,438

Large GWAS

European

Okbay A et al. “Genome-wide association study identifies 74 loci associated with educational attainment.” Nature 533(7604):539-42 (2016)

Allele T

OR —

β 0.017

p 3.0e-14

N 405,072

Large GWAS

European

Alzheimer disease, educational attainment

Kulminski AM et al. “Pleiotropic predisposition to Alzheimer's disease and educational attainment: insights from the summary statistics analysis.” Geroscience 44(1):265-280 (2022)

Allele T

OR 53.84

p 6.0e-11

N 4,029

Large GWAS

smoking status measurement

Liu M et al. “Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.” Nature Genetics 51(2):237-244 (2019)

Allele T

OR 0.02

p 2.0e-18

N 1,232,091

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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