rs10099237

This is a intron variant variant in the RGS22 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

non-melanoma skin carcinoma

Visconti A et al. “Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure.” Nature Communications 9(1):1684 (2018)

Allele C

OR 1.22

p 5.0e-13

N 187,652

Large GWAS

About RGS22

Enables G-protein alpha-subunit binding activity. Predicted to be involved in negative regulation of signal transduction. Located in actin cytoskeleton; cytosol; and fibrillar center. [provided by Alliance of Genome Resources, Jul 2025]

View all RGS22 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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