rs10145740

GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

cholesteryl esters in medium HDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.02
p 4.0e-22
N 450,015
Large GWAS
multi-ancestry

cholesterol in medium HDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.02
p 1.0e-21
N 450,015
Large GWAS
multi-ancestry

apolipoprotein B to apolipoprotein A1 ratio

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.02
p 7.0e-11
N 450,015
Large GWAS
multi-ancestry

glomerular filtration rate

Allele T
OR 6.29
p 3.0e-10
N 1,508,659
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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