rs10157710

This is a downstream gene variant variant.

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GWAS Catalog Trait Associations (6)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

level of hypoxia up-regulated protein 1 in blood

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.07
p 2.0e-26
N 47,745
Large GWAS
European

protein kinase C-binding protein NELL1 measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.06
p 8.0e-20
N 47,745
Large GWAS
European

aggrecan core protein measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.05
p 5.0e-16
N 47,745
Large GWAS
European

urinary albumin to creatinine ratio

Zanetti D et al. “Identification of 22 novel loci associated with urinary biomarkers of albumin, sodium, and potassium excretion.” Kidney International 95(5):1197-1208 (2019)
Allele T
OR 0.03
p 1.0e-13
N 218,759
Large GWAS
European

interleukin-10 receptor subunit beta measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.05
p 2.0e-13
N 47,745
Large GWAS
European

albuminuria

Haas ME et al. “Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure.” American Journal of Human Genetics 103(4):461-473 (2018)
Allele T
OR 0.02
p 3.0e-13
N 302,687
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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