rs10191758
This is a regulatory region variant variant in the ARHGAP15 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
intelligence
Sniekers S et al. “Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence.” Nature Genetics 49(7):1107-1112 (2017)
Allele A
OR 5.93
p 3.0e-9
N 78,308
Meta-analysisLarge GWAS
European
post-traumatic stress disorder
Nievergelt CM et al. “Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder.” Nature Genetics 56(5):792-808 (2024)
Allele A
OR 5.52
p 3.0e-8
N 1,280,933
Large GWAS
multi-ancestry
About ARHGAP15
RHO GTPases (see ARHA; MIM 165390) regulate diverse biologic processes, and their activity is regulated by RHO GTPase-activating proteins (GAPs), such as ARHGAP15 (Seoh et al., 2003 [PubMed 12650940]).[supplied by OMIM, Mar 2008]
View all ARHGAP15 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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