rs10206899

This is a intron variant variant in the ALMS1P1 gene.

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GWAS Catalog Trait Associations (7)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

N-acetylornithine measurement

Shin SY et al. “An atlas of genetic influences on human blood metabolites.” Nature Genetics 46(6):543-550 (2014)
Allele T
OR 0.22
p —
N 7,574
Large GWAS
European

glomerular filtration rate

Stanzick KJ et al. “Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals.” Nature Communications 12(1):4350 (2021)
Allele T
OR 0.01
p 2.0e-123
N 1,201,930
Large GWAS
multi-ancestry
Tin A et al. “Using multiple measures for quantitative trait association analyses: application to estimated glomerular filtration rate.” Journal of Human Genetics 58(7):461-6 (2013)
Allele T
OR 1.17
p 4.0e-8
N 9,049
Large GWAS
European

X-11787 measurement

Shin SY et al. “An atlas of genetic influences on human blood metabolites.” Nature Genetics 46(6):543-550 (2014)
Allele T
OR 0.04
p 8.0e-123
N 7,811
Large GWAS
European

alliin measurement

Chen Y et al. “Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases.” Nature Genetics 55(1):44-53 (2023)
Allele C
OR 0.43
p 4.0e-97
N 6,517
Large GWAS
European

serum creatinine amount

Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)
Allele C
OR 0.04
p 7.0e-72
N 494,370
Large GWAS
multi-ancestry
Chambers JC et al. “Genetic loci influencing kidney function and chronic kidney disease.” Nature Genetics 42(5):373-5 (2010)
Allele C
OR 1.00
p 1.0e-15
N 23,812
Large GWAS
European

metabolite measurement

Schlosser P et al. “Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine.” Nature Genetics 55(6):995-1008 (2023)
Allele C
OR 0.22
p 1.0e-31
N 2,607
Large GWAS
European

X-13477 measurement

Shin SY et al. “An atlas of genetic influences on human blood metabolites.” Nature Genetics 46(6):543-550 (2014)
Allele T
OR 0.03
p 2.0e-14
N 5,952
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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