rs10207567
This is a intron variant variant in the ICA1L gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
urinary albumin to creatinine ratio
Teumer A et al. “Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.” Nature Communications 10(1):4130 (2019)
Allele C
OR 0.02
p 3.0e-14
N 547,361
Large GWAS
European
Casanova F et al. “A genome-wide association study implicates multiple mechanisms influencing raised urinary albumin-creatinine ratio.” Human Molecular Genetics 28(24):4197-4207 (2019)
Allele C
OR 0.02
p 2.0e-12
N 437,027
Large GWAS
European
albuminuria
Haas ME et al. “Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure.” American Journal of Human Genetics 103(4):461-473 (2018)
Allele C
OR 0.01
p 1.0e-11
N 382,500
Large GWAS
European
smoking status measurement
Liu M et al. “Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.” Nature Genetics 51(2):237-244 (2019)
Allele C
OR 0.01
p 1.0e-10
N 1,359,002
Large GWAS
European
About ICA1L
Predicted to enable protein domain specific binding activity. Predicted to be involved in regulation of transport. Predicted to act upstream of or within spermatid development. Predicted to be located in acrosomal vesicle. Predicted to be active in Golgi apparatus. [provided by Alliance of Genome Resources, Jul 2025]
View all ICA1L variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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