rs10209482

This is a intron variant variant in the ZRANB3 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

gut microbiome measurement

Kurilshikov A et al. “Large-scale association analyses identify host factors influencing human gut microbiome composition.” Nature Genetics 53(2):156-165 (2021)

Allele C

OR 6.04

p 2.0e-9

N 18,340

Large GWAS

multi-ancestry

About ZRANB3

Enables ATP-dependent DNA/DNA annealing activity; DNA endonuclease activity; and K63-linked polyubiquitin modification-dependent protein binding activity. Involved in DNA repair; replication fork reversal; and response to UV. Located in nuclear replication fork and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]

View all ZRANB3 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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