rs10213171

This is a intron variant variant in the ARHGAP10 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

atrial fibrillation

Miyazawa K et al. “Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction.” Nature Genetics 55(2):187-197 (2023)

Allele G

OR 0.10

p 6.0e-18

N 2,339,188

Large GWAS

multi-ancestry

Nielsen JB et al. “Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.” Nature Genetics 50(9):1234-1239 (2018)

Allele G

OR 1.10

p 1.0e-11

N 1,030,836

Large GWAS

European

Roselli C et al. “Multi-ethnic genome-wide association study for atrial fibrillation.” Nature Genetics 50(9):1225-1233 (2018)

Allele G

OR 1.11

p 6.0e-14

N 588,190

Large GWAS

multi-ancestry

About ARHGAP10

Predicted to enable GTPase activator activity. Predicted to be involved in cytoskeleton organization and negative regulation of apoptotic process. Located in cytosol and endosome membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all ARHGAP10 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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